QT Imaging has reported reproducibility results for the quantitative biomarkers generated by its QT Imaging Breast Acoustic CT scanner.
The radiation-free breast imaging platform's speed of sound (SoS) measurement achieved variability -- measured as within-subject coefficient of variation (wCV) -- of less than 1% both within a single scanner and across scanners, according to the company. Volumetric measurements derived from SoS image volumes showed variability of about 5% for total breast volume and 12% for the ratio of fibroglandular volume to total breast volume, QT said. The analysis was conducted at two clinical sites, with five patients enrolled per site and each patient scanned five times.
By comparison, the firm noted that published benchmarks place the repeatability coefficient for breast MRI apparent diffusion coefficient (ADC) measurements in the range of about 13% to 15%, while separately reported test-retest variability for ADC was approximately 11%.
QT Imaging said the level of reproducibility supports the use of its quantitative biomarkers for longitudinal monitoring over time.
