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A Ibrain
Molecular Imaging
PET reveals brain receptor deficits in schizophrenia
The study confirms that deficits in M1 receptor are present in a subgroup of schizophrenia patients.
Caption: Representative images show emphysema and functional lung maps derived by CT and PREFUL-MRI: (A–C) CT-derived emphysema images, (D–F) perfusion maps, (G–I) regional ventilation maps, (J–L) flow-volume loop correlation metric maps, (M–O) ventilation/perfusion combined parameter maps. (A, D, G, J, M) Images in a 63-year-old male with normal spirometry: FEV1%pred = 89.0%, FEV1/FVC = 0.73; emphysema percentage = 0.2%, QDP = 7%, VDPRVent = 2%, VDPFVL-CM = 1%. (B, E, H, K, N) Images in a 65-year-old female with PRISm + RP: FEV1%pred = 71.2%, FVC %pred = 76.8%, FEV1/FVC = 0.76; emphysema percentage = 4.7%, QDP = 10%, VD-PRVent = 18%, VDPFVL-CM = 6%. (C, F, I, L, O) Images in a 57-year-old male with AO: FEV1%pred = 56.8%, FEV1/FVC = 0.52; emphysema = 11.1%, QDP = 31%, VDPRVent = 33%, VDPFVL-CM = 41%. AO = airflow obstruction, FEV1 = forced expiratory volume in 1 second, FVC = forced vital capacity, FVL-CM = flow-volume loop correlation metric, %pred = percent predicted, PREFUL = phase-resolved function lung, PRISm = preserved ratio impaired spirometry, QDP = perfusion defect percentage, RVent = regional ventilation, VDP = ventilation defect percentage.
MRI
MRI finds perfusion defects across a range of lung impairments
Am 2020 06 26 16 29 2945 Cancer Lung 400
CT
AI detects lung cancer nodules well but shows low specificity
Lab Equipment Drug Manufacturing
Molecular Imaging
Radiopharmaceutical manufacturers report uneven FDA inspections
AI for CT & PET/CT Imaging
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AI for CT & PET/CT Imaging
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AI approach could improve DBT efficiency
By Amerigo Allegretto
AI-based slab reconstruction may help improve screening DBT workflows while not compromising on image quality.
June 2, 2026
Slab reconstruction provides visualization of subtle architectural distortion similar to that of standard 1-mm slices in a false-positive screening exam. Images include breast exams from a 45-year-old woman who underwent screening mammography. Craniocaudal tomosynthesis images with (A) 1-mm slices and (B) 6-mm slab reconstructions show an area of architectural distortion in the subareolar region of the left breast (arrow). (C) Targeted ultrasound imaging shows a corresponding irregular hypoechoic mass (arrow), which was subsequently biopsied. Pathologic examination revealed a sclerosing papillary lesion.
SNMMI: Incoming president talks meeting highlights, previews next year
By Kate Madden Yee
AuntMinnie.com interviewed incoming SNMMI president Heather Jacene, MD.
June 2, 2026
Heather Jacene, MD
SNMMI: Biomarkers predict I-131 response in obese thyroid cancer patients
By Kate Madden Yee
Metabolic status should be considered in post-therapy evaluation of obese differentiated thyroid cancer patients, researchers noted.
June 2, 2026
Snmmi Thumb
Podcast: Telltale signs your MRI safety standards are inadequate
By Liz Carey
Check your MRI safety sense.
June 2, 2026
The Invisible Force Podcast Album Cover Auntminnie Jan 2026 Thumbnails
SNMMI: Theranostic approach may treat PSMA-negative prostate cancer
By Amerigo Allegretto
A theranostic approach could help improve PET imaging for neuroendocrine prostate cancer care.
June 2, 2026
RET-targeted PET tracer highlights neuroendocrine prostate cancer tumors. Representative PET imaging shows strong tumor uptake of the RET-binding peptide tracer [⁶⁸Ga]Ga-DOTA-RET-L7 in a neuroendocrine prostate cancer (NEPC) model, supporting highly specific, high-contrast detection.
ASCO: Use of GLP-1 drugs linked to lower breast cancer cases
By Erik L. Ridley
A large retrospective study found sharply lower incidence of breast cancer among women who had received GLP-1 drugs.
June 2, 2026
Asco Thumb
SNMMI: CAIX-targeted PET tracer detects clear cell renal cell carcinoma
By Liz Carey
Researchers aim for "more precise molecular map" for kidney cancer.
June 1, 2026
A 68Ga-RCC78 PET scan (C) of a patient four years post-radical right nephrectomy. During follow-up, new nodules were detected in the left adrenal gland and kidney. CAIX-targeted scan clearly visualized metastatic lesions in the mediastinum, pancreas, adrenal gland, and kidney (SUVmax > 30), demonstrating the tracer's ability to maintain high tumor uptake despite significantly reduced abdominal background.
SNMMI: Low-cost absorbents clear over 90% of Lu-177 from wastewater
By Kate Madden Yee
An increase in the use of radionuclide therapy has added burden to wastewater management systems.
June 1, 2026
Snmmi Thumb
SNMMI: PET tracer that detects deep vein thrombosis wins Image of the Year
By Will Morton
F-18 GP1 is derived from elarofiban and selectively binds to glycoprotein IIb/IIIa receptors on activated platelets.
June 1, 2026
(Left) F-18 GP1 PET/CT images from a 75-year-old woman show multiple blood clots in the deep veins of the left leg (from the thigh to the calf), as well as several clots in the right calf. Venous ultrasound confirms blood clots in left thigh, knee and calf veins. PET/CT also detects clots in both lungs, which are confirmed by contrast-enhanced CT image. (Right) 18F-GP1 PET/CT images from a 70-year-old woman show widespread blood clots throughout the body. In addition to clots in the deep veins of both legs and the arteries of both lungs (A), the scan also detected unexpected clots in several other areas, including blood vessels near the skull/head (B), spine (C), heart (D), and pelvis (E). Further evaluation revealed that the patient had antiphospholipid syndrome, an autoimmune condition that increases the risk of abnormal blood clot formation.
SNMMI: Novel radiotracer effectively images overactive adrenal glands
By Liz Carey
University of Michigan researchers report on first-in-human study of SOAT1-targeted nevanimibe C-11.
June 1, 2026
Static PET-CT image of patient with hypercortisolism taken at 60 minutes post-injection.
SNMMI: Mouaz Al-Mallah discusses cardiac PET
By Will Morton
In this interview, Mouaz Al-Mallah, MD, discusses cardiac PET imaging, including new efforts to create more access for patients and the impact of new radiotracers.
June 1, 2026
Mouaz Al Mallah Thumb1
ASCO: Proton therapy, IMRT both work well for prostate cancer
By Erik L. Ridley
Both modalities yielded similar outcomes, according to preliminary results from a large, prospective trial.
June 1, 2026
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