Will Morton

[email protected]

Nongated CT scans can predict heart disease risk

Subjects with moderate and severe CAC scores on nongated CT had significantly higher risk of coronary heart disease risk.

July 30, 2026

CT radiation doses have fallen sharply over past decade

The largest reductions appeared in chest examinations with contrast material, where diagnostic reference levels fell 31%.

July 28, 2026

Bar graphs show comparison of volume CT dose index (CTDIvol) (A) achievable doses (50th percentile) and (B) diagnostic reference levels (75th percentile) between 2014 (see reference 4 by Kanal et al) and 2025 (present study) for 10 common CT examination types performed without contrast (w/o) and with contrast (w/). Across all 10 adult CT examination categories, CTDIvol achievable doses and diagnostic reference levels generally decreased from 2014 to 2025, with the largest reductions for torso examinations (chest; abdomen-pelvis; and combined chest, abdomen, and pelvis), intermediate reductions for neck and cervical spine, and minimal change for head examinations.

Molecular Imaging

SPECT/CT viable over PET/CT for high-risk prostate cancer staging

Considering its broader accessibility, Tc-99m MIP-1404 CZT SPECT/CT may represent a practical alternative for primary staging.

July 24, 2026

Maximum intensity projection of Ga-68 PSMA-11 PET/CE-CT (A), Tc-99m MIP-1404 CZT SPECT/CT (B) and Tc-99m HDP CZT SPECT/CT (C) imaging. Ga-68 PSMA-11 PET/CE-CT and Tc-99m MIP-1404 CZT SPECT/CT showing tracer uptake in lymph nodes below the iliac bifurcation and above, paraaortic and left supraclavicular, bone uptake in the right proximal femur and right scapula (arrows). Tc-99m HDP CZT SPECT/CT did not show any uptake suspicious for metastatic disease. No sclerotic lesions suspicious of metastases were detected by the CT component in any of the studies. Fusion axial imaging of Ga-68 PSMA-11 PET/CE-CT (D) and Tc-99m MIP-1404 CZT SPECT/CT (E) showing uptake in lymph nodes in the left pelvic area below the iliac bifurcation (arrows). Fusion axial imaging of Ga-68 PSMA-11 PET/CE-CT (F) and Tc-99m MIP-1404 CZT SPECT/CT (G) showing uptake in the right proximal femur, not detected by Tc-99m HDP CZT SPECT/CT (H), (arrows).

AuntMinnie.com Molecular Imaging Insider

In this edition of the Molecular Imaging Insider, we’ve highlighted a study showing that Lutetium-177 PSMA-617 spots early signs of benefit in men with metastatic hormone-sensitive prostate cancer.

July 21, 2026

Nuclear Medicine

Lutetium-177 PSMA-617 shows promise in earlier-stage prostate cancer

Across 14 studies, PSA50 response rates (the number of patients with at least a 50% drop in PSA) ranged from 44% to 100%.

July 21, 2026

Prostate Imaging

LDCT screening criteria miss majority of Korean lung cancer patients

Just 35.4% of patients diagnosed with lung cancer met the 2023 American Cancer Society (ACS) screening criteria.

July 21, 2026

CT reveals severe craniofacial, ocular trauma from pager blasts

Head injuries were nearly universal, affecting 93.2% of patients.

July 20, 2026

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Molecular Imaging

Brain PET scans reveal neuron loss in long COVID

The findings suggest that treatments aimed at boosting dopamine release could be repurposed to treat long COVID.

July 14, 2026

Representative participant from each group shown. C-11 DTBZ non-displaceable binding potential (BPND) in voxels quantitated with simplified reference tissue model 2. Color scale indicates C-11 DTBZ BPND from 0 (black) to 3.5 (red), with reduced C-11 DTBZ BPND observed in the long COVID case compared to both healthy controls.

First human x-rays in space deemed diagnostic

Crew surveys identified alignment and positioning, including of the subject, x-ray source, and detector, as the primary operational challenges.

July 14, 2026

Representative preflight, in-flight, and postflight chest radiographs. Radiographs of the chest were acquired (A) preflight by a crewmember, (B, C) in-flight on day 3 after launch (L+3) by a crewmember, and (D) postflight by a non-crew operator using the same imaging protocol.

New criteria evaluates treatment response in bone metastases

RECIBM-defined response classifications showed high agreement with established criteria and reclassified 19% of patients.

July 7, 2026

Response Evaluation Criteria in Bone Metastases (RECIBM) and metabolic criteria were used to detect a complete response missed at anatomic assessment. A 76-year-old male patient presented with 1 month of hemoptysis and was diagnosed with small cell lung cancer and bone metastases. Baseline (July 2022) F-18 FDG-PET/CT images (A, maximum intensity projection image; B–E, axial images) demonstrate FDG-avid lesions in the left lamina of the first lumbar vertebra (L1) (straight yellow arrows; maximum standardized uptake value, 2.74; peak standardized uptake value normalized to lean body mass, 1.59) and left ilium (curved yellow arrows; maximum standardized uptake value, 3.68; peak standardized uptake value normalized to lean body mass, 2.28). After seven chemotherapy cycles (December 2022), follow-up PET/CT images (F, maximum intensity projection image; G–J, axial images) show complete metabolic resolution of bony lesions (L1: maximum standardized uptake value, 1.32, and peak standardized uptake value normalized to lean body mass, 0.85; left ilium: maximum standardized uptake value, 1.48, and peak standardized uptake value normalized to lean body mass, 0.82), without apparent osteolytic or osteoblastic changes at CT. Assessment was stable disease (SD) according to the University of Texas MD Anderson Cancer Center (MDA) criteria but complete response (CR) or complete metabolic response (CMR) according to RECIBM, PET Response Criteria in Solid Tumors (PERCIST), and European Organization for Research and Treatment of Cancer (EORTC) criteria. The patient was alive as of September 30, 2025.

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Food Insecurity

Food insecurity linked to higher risk of death in breast cancer

Food-insecure regions are where people lack consistent access to enough affordable, nutritious food.

Mri Slide 400

How much surveillance imaging is needed for meningiomas?

Minnie Cast Thumbnail (20)

Ultrasound MinnieCast, Episode 15: Wearable ultrasound making strides

True-positive PSMA-PET with positive MRI in 74-year-old male with prostate cancer (Gleason score of 4 + 5; left anterior and posterior apex positive cores). (A) Left posterior peripheral apical to midprostate hyposignal visible on transaxial MRI. (B) No definite CT correlate evident (white arrow). (C) Focal high PSMA expression detectable in left posterior mid to base with SUVmax of 12.4 on transaxial fused delayed pelvic PET/CT (yellow arrow). (D) Focal high PSMA expression found in left midgland to base of prostate on maximum-intensity-projection image (yellow arrow).

PET/CT outperforms MRI after focal therapy for prostate cancer

Nominations Are Open — 2026 Minnies

Nominations Are Open — 2026 Minnies

CT for breast radiotherapy detects ischemic heart disease risk

As survival after early-stage breast cancer improves, cardiovascular disease has emerged as an increasingly prominent competing risk in older women.

August 17, 2026

MWA may have long-term benefits for renal cell cancer patients

By Amerigo Allegretto

MWA with CT or CEUS guidance leads to "excellent" 10-year survival rates and with minimal complications.

August 17, 2026

Radiation-related cancer mortality higher for U.S. flight crew

By Amerigo Allegretto

Results point to prolonged exposure to cosmic radiation at commercial flight attitudes.

August 17, 2026

Airplane Takeoff 400

AI system cuts DEXA turnaround time, improves reports

Median report creation and turnaround times dropped to under one minute.

August 14, 2026

PAE effective in men over 80 years old

Findings support PAE as an important minimally invasive treatment option for elderly patients who are nonsurgical candidates.

August 14, 2026

Prostate Imaging2

Prone positioning may benefit women undergoing PBI

By Amerigo Allegretto

Prone positioning may lead to lower heart and lung doses and lower rates of acute dermatitis.

August 14, 2026

Radiation Therapy Suite 400

Lantheus wins FDA approval for tau PET imaging agent

By AuntMinnie.com staff writers

Tauklarify, previously known as MK-6240, has been approved for tau PET imaging in adults with cognitive impairment being evaluated for Alzheimer's disease.

August 14, 2026

Approved Stamp 400

Women's Imaging MinnieCast, Episode 15: BACs and heart disease risk

By Amerigo Allegretto

Laurie Margolies, MD, shares insights on how breast arterial calcifications (BACs) on mammograms should be managed.

August 14, 2026

Minnie Cast Thumbnail (19)

FAPI-PET/CT shows promise in hepatopancreatobiliary cancers

FAPI-PET/CT could potentially improve noninvasive cancer staging, and, ultimately, clinical decision making.

August 13, 2026

Shown is a 69-year-old man with a cholangiocarcinoma in the distal common bile duct. F-18 FDG-PET/CT was negative where Ga-68 FAPI-46 PET/CT showed high focal FAPI uptake in the liver hilum and surrounding lymph nodes. a-d: F-18 FDG-PET/CT, e-h: Ga-68 FAPI-46 PET/CT. a, b, e, f: Maximum intensity projections, c, g: axial fusion images, d, h: non-contrast enhanced CT.

Longitudinal DBT could help improve long-term cancer risk prediction

By Amerigo Allegretto

A longitudinal DBT model outperformed other models based on mammography and clinical factors in predicting five-year cancer risk.

August 13, 2026

SBRT for prostate cancer cuts side effects, falls short on disease control

A multinational team evaluated SBRT against moderately hypofractionated intensity-modulated radiation therapy in a phase III trial.

August 13, 2026

Prostate Imaging

DEXA reveals tea consumption supports bone health

Moderate-frequency tea consumption was associated with better bone mineral status and more favorable longitudinal changes.

August 12, 2026

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