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Will Morton

[email protected]
Molecular Imaging
NET tracers first widened, then closed imaging access gap
Ga-68 DOTATATE/DOTATOC captured 33.8% market share in its 2017 debut and reached 90.9% by 2020.
April 30, 2026
Adobe Stock 107601498
Molecular Imaging
Lu-177 PSMA-SPECT/CT predicts survival in mCRPC
Lu-177 PSMA-617 SPECT/CT total tumor volume complete response at six weeks associated with overall survival.
April 29, 2026
Quantification of total tumor volume (TTV) at lutetium-177 prostate-specific membrane antigen (PSMA)–617 SPECT/CT shows heterogeneous TTV responses between dose 1 (Cycle #1) and dose 2 (Cycle #2) in participants with metastatic castration-resistant prostate cancer. Posttherapy coronal attenuation-corrected noncontrast SPECT/CT maximum intensity projection images demonstrate (A) near-complete response in a 76-year-old man, (B) complete response in an 83-year-old man, (C) partial TTV reduction (not complete response) in a 69-year-old man, and (D) TTV increase (i.e. progressive disease) in a 74-year-old man. Blue-shaded regions represent semiautomatically segmented PSMA-avid tumor volume, with associated TTV values given at the bottom of each panel. The gradient bar shows standardized uptake value (SUV) from 0 to 5.
AI
Children ‘almost invisible’ in public imaging datasets
Among 135 datasets with usable age data, children accounted for just 6,026 of 512,608 patients (under 2%).
April 27, 2026
Children
Molecular Imaging
ChatGPT matches nuclear medicine experts on FDG-PET/CT scans
Models excelled on cases with well-defined metabolic patterns, such as in typical cases of Alzheimer's disease, yet were less accurate on complex cases.
April 24, 2026
Ai Face
Practice Management
Musculoskeletal strain affects majority of radiologists
Musculoskeletal strain represents the single largest category of workplace injury in radiology.
April 23, 2026
Ergonomics
Interventional
GAE benefits may just be ‘placebo effect’
Patients who received either genicular artery embolization (GAE) or a sham procedure experienced equal pain improvements.
April 22, 2026
Contrast-enhanced T1 weSPGR images of the knee of a patient from the GAE group at the level of the suprapatellar recess. The baseline image (left) shows a marked synovial enhancement. There was no change one month after treatment (middle image) and four months after treatment (right image).
Molecular Imaging
FDG-PET predicts outcomes in metastatic breast cancer
Patients without disease progression on FDG-PET scans 14 days after treatment had better progression-free and overall survival.
April 16, 2026
Breast Cancer Social
Molecular Imaging
ARRS: Do GLP-1 drugs confound FDG-PET imaging scans?
No significant differences in FDG uptake were observed in the skeletal muscle, liver, blood pool, or abdominal fat following GLP-1 agonist therapy.
April 13, 2026
Patient Pet
Molecular Imaging
PET links brain metabolism to survival in lung cancer patients
Low brain metabolic activity was associated with increased mortality in patients with advanced NSCLC.
April 9, 2026
A visual abstract of the study
AI
AI aging estimates based on chest x-rays linked to mortality
No studies have investigated the ability of aging velocity -- the rate of change in radiographic age over time -- to predict mortality.
April 3, 2026
Artificial Intelligence Ai Abstract Social
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A graphical abstract of the study.
Molecular Imaging
FDG-PET/CT predicts outcomes in patients with HCC
Elevated FDG uptake was consistently associated with poorer overall survival.
Brain Abstract
MRI
Multimodal brain health composites outperform standard AD biomarkers
Breast Mammo 400 (1)
Womens Imaging
CEM shows strong performance in diagnosing DCIS
Minnie Cast Thumbnail 22 May
Podcast Network
Women's Imaging MinnieCast, Episode 9: Katja Pinker and breast MRI
The Wedding Was Easy. The Marriage Is the Work.
Sponsor Content
The Wedding Was Easy. The Marriage Is the Work.
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MRI-based ML model shows promise in colorectal cancer subtyping
By Amerigo Allegretto
A machine-learning model based on MRI radiomics achieved high performance in predicting colorectal cancer subtypes.
May 19, 2026
Overview of the study design, including data collection, radiomics model construction, and biologic interpretation. (A) The primary cohort for model development and evaluation in the training and internal test sets includes 168 patients with colorectal cancer (CRC) from center 1 (Fudan University Shanghai Cancer Center), whereas external testing was performed using data from 85 patients from centers 2 (Huashan Hospital, Fudan University) and 3 (Zhongshan Hospital, Fudan University). For model interpretation, RNA sequencing (RNA-seq) data from 18 patients with CRC in center 1 and single-cell data from 35 patients from the Gene Expression Omnibus (GEO) database are incorporated. Mismatch repair (MMR) protein expression, obtained from pathologic reports in electronic medical records (EMRs), was used to identify patients with consensus molecular subtype 1 (CMS1) CRC. Tissue microarrays (TMAs) from surgically obtained CRC tissues were analyzed for immunohistochemical staining of caudal-type homeobox 2 (CDX2), 5-hydroxytryptamine receptor 2B (HTR2B), FERM domain containing 6 (FRMD6), and zinc finger E-box binding homeobox 1 (ZEB1), and the results were subsequently entered into an online classification tool that assigned patients to CMS2, 3, or 4 subtypes. (B) Radiomics workflow for CMS4 prediction. Lesions were manually delineated on T2-weighted imaging (T2WI) and contrast-enhanced (CE) T1-weighted imaging (T1WI), followed by radiomics feature extraction. Feature selection and model development were performed in the training set using machine-learning algorithms with fivefold cross-validation for model selection, and the final model was evaluated in the internal and external test sets using receiver operating characteristic (ROC) curve analysis. (C) Transcriptomic interpretation workflow. Using the radiomics-predicted CMS4 classification, bulk RNA sequencing (RNA-seq) data were used to perform differential expression analysis between predicted CMS4 and non-CMS4 groups, followed by pathway enrichment analyses to assess biologic relevance. Public single-cell RNA sequencing data from the Gene Expression Omnibus database were then used for cell-type–level interrogation to support interpretation of the associated pathways.
Podcast: Expert witness hats come out to begin closing investigation
By Liz Carey
The episode the hosts have eagerly anticipated.
May 19, 2026
The Invisible Force Podcast Album Cover Auntminnie Jan 2026 Thumbnail sra O0 D Ij Z6
Almost half of families face financial hardship from kids' scans
By Kate Madden Yee
These families are more than three times as likely to delay or skip recommended scans because of cost.
May 19, 2026
Mri Scanner Kid
Combined fluoride and lead exposure reduces bone health in youth
By Will Morton
Co-exposure to fluoride and lead exacerbates changes in BMD more than single exposure, suggesting synergistic effects on bone impairment.
May 18, 2026
A graphical abstract of the study.
Medical societies applaud proposed CEUS training recommendations
By Amerigo Allegretto
Ultrasound societies are voicing support for new proposed training standards by CAAHEP for CEUS education.
May 18, 2026
Contrast Injector 400
Cochrane updates 2013 prostate cancer screening review
By Kate Madden Yee
Standard PSA screening has a well-known weakness: it catches many slow-growing cancers that would never have caused harm, Cochrane said.
May 18, 2026
Prostate
ISMRM: fMRI flags brain network failures in fibromyalgia, long COVID
By Kate Madden Yee
While both conditions demonstrate reduced brain network flexibility, the underlying mechanisms differ.
May 18, 2026
Muscle Trigger Points Sized
ISMRM: PET/MRI highly effective in patients with atherosclerosis
By Will Morton
PET/MRI distinguished symptomatic from asymptomatic carotid plaques among 145 patients.
May 15, 2026
Multimodality imaging (MRI, PET, and fused PET/MRI) of carotid artery plaques in asymptomatic and symptomatic subjects, illustrating distinct features of surface ulceration, plaque enhancement, metabolic uptake, and SUVmax.
ISMRM: Researchers eye fibrosis patterns in the body's organs
By Liz Carey
Quantitative measures obtained from MRIs enable fibrotic scoring system, according to group.
May 15, 2026
Fibrotic Buckets Disease Inclusion Uk Biobank Population Ismrm2026
ISMRM: PET/MRI-guided treatment reduces low back pain
By Will Morton
This study is the first to acquire follow-up FDG-PET/MRI scans after treatment to assess the correlation between clinical outcome and FDG uptake.
May 15, 2026
A 70-year-old female patient with chronic low back pain. History of radicular syndrome which led to targeted nerve block with positive effect. However, lower back pain persisted. FDG-PET/MRI showed increased FDG uptake in a disc herniation at L5-S1 (SUVmax 1.6) convincing the treating physician to proceed to discectomy. After discectomy, the patient is now mostly pain free.
ISMRM: MRI-based AI predicts organ aging before disease signs emerge
By Kate Madden Yee
A DL model combining MRI scans with blood markers, imaging biomarkers, and lifestyle data can predict organ-specific biological age.
May 15, 2026
Ismrm Thumbnail
Ultrasound MinnieCast, Episode 8: Ultrasound's role in sustainability
By Amerigo Allegretto
Researchers from VUMC share results and strategies from their study on ultrasound's role in environmental sustainability.
May 15, 2026
Minnie Cast Thumbnail 15 May
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