Digital x-ray company Nanox’s artificial intelligence (AI) subsidiary Nanox.AI has received U.S. Food and Drug Administration (FDA) 510(k) clearance for HealthOST, an AI-based software application for qualitative and quantitative analysis of CT spine imaging.
HealthOST provides fully automated spinal analysis of vertebral compression fractures and low bone density often associated with osteoporosis to support clinicians in the evaluation and assessment of musculoskeletal disease, according to the vendor.
The FDA clearance is Nanox.AI's 10th across its portfolio of AI clinical-decision assistance tools and its second clearance for vertebral compression fracture detection software, Nanox said.
![Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/06/hanneman.r6SMLzkezo.png?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
