Dr. Robert Freed

CT
Second Take: Must patients really be warned of radiation risk?
Should radiologists be required to get informed consent from patients before they undergo medical imaging procedures involving radiation? In this Second Take column, radiologists from the University of Pittsburgh assert that such notification is not only burdensome, it undermines the delivery of quality medical care.
December 17, 2013
2013 07 30 12 53 25 294 Second Take Am 200
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(A) Overview of study participants with different clinical phenotypes depicted in distinct colors: Limbic encephalitis (LE)/temporal lobe epilepsy (TLE): Blue; cerebellar ataxia (CA): Green; stiff person syndrome (SPS): Red, including overlapping clinical features with an overview of the analyzed parameter; generated in Biorender. (B) F-18 F-DED uptake, as visualized by SUVr with global mean scaling, is shown for three representative patients with GAD65-AIE: Patient #6 with LE/TLE, showing mesiotemporal F-18 F-DED uptake; patient #16 with overlapping clinical features of CA, SPS, and LE, showing both mesiotemporal and cerebellar F-18 F-DED uptake; and patient #17 with isolated SPS showing no increased F-18 F-DED uptake. Additionally, the average F-18 F-DED uptake of eight controls is shown on the right.
Molecular Imaging
PET reveals disease activity in autoimmune encephalitis
PET revealed brain region-specific astrogliosis corresponding to clinical manifestations and disease severity.
Mammography Tech Woman 400
Womens Imaging
Mammography use declining among women
Representative images of participants with difficulty with breath holding and arrhythmia. In the lower right corner of A–L, the position coordinates of the images are marked. Short-axis (SA) view images in the end-systole (A–F) and end-diastole (G–L) phases in participants with atrial fibrillation. (A–C, G–I) Balanced steady-state free precession (bSSFP) cardiac cine. (D–F, J–L) Deep learning–enhanced compressed sensing (AI-CS) single-shot cardiac cine. In contrast to AI-CS single-shot cardiac cine, endocardial contours were challenging to identify on conventional segmented cine in midventricular and apical sections. (M) Line graph of time curve during the whole cardiac cycle obtained from bSSFP cardiac cine. (N) Line graph of time curve during the whole cardiac cycle obtained from AI-CS single-shot cardiac cine. LV = left ventricle; 2D = two-dimensional.
MRI
Novel AI-enhanced MRI algorithm helps assess left ventricular function
Ovary
Interventional
Sclerotherapy spares ovarian reserve without loss of therapeutic efficacy
Modernizing Radiotherapy Workflows
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PET reveals disease activity in autoimmune encephalitis
By Will Morton
PET revealed brain region-specific astrogliosis corresponding to clinical manifestations and disease severity.
March 26, 2026
(A) Overview of study participants with different clinical phenotypes depicted in distinct colors: Limbic encephalitis (LE)/temporal lobe epilepsy (TLE): Blue; cerebellar ataxia (CA): Green; stiff person syndrome (SPS): Red, including overlapping clinical features with an overview of the analyzed parameter; generated in Biorender. (B) F-18 F-DED uptake, as visualized by SUVr with global mean scaling, is shown for three representative patients with GAD65-AIE: Patient #6 with LE/TLE, showing mesiotemporal F-18 F-DED uptake; patient #16 with overlapping clinical features of CA, SPS, and LE, showing both mesiotemporal and cerebellar F-18 F-DED uptake; and patient #17 with isolated SPS showing no increased F-18 F-DED uptake. Additionally, the average F-18 F-DED uptake of eight controls is shown on the right.
Mammography use declining among women
By Amerigo Allegretto
Non-Hispanic white, Asian, and uninsured women ages 40 to 49 years used mammography less between 2010 and 2022.
March 26, 2026
Mammography Tech Woman 400
Novel AI-enhanced MRI algorithm helps assess left ventricular function
By Kate Madden Yee
A study's findings could improve imaging results for patients with arrythmia.
March 26, 2026
Representative images of participants with difficulty with breath holding and arrhythmia. In the lower right corner of A–L, the position coordinates of the images are marked. Short-axis (SA) view images in the end-systole (A–F) and end-diastole (G–L) phases in participants with atrial fibrillation. (A–C, G–I) Balanced steady-state free precession (bSSFP) cardiac cine. (D–F, J–L) Deep learning–enhanced compressed sensing (AI-CS) single-shot cardiac cine. In contrast to AI-CS single-shot cardiac cine, endocardial contours were challenging to identify on conventional segmented cine in midventricular and apical sections. (M) Line graph of time curve during the whole cardiac cycle obtained from bSSFP cardiac cine. (N) Line graph of time curve during the whole cardiac cycle obtained from AI-CS single-shot cardiac cine. LV = left ventricle; 2D = two-dimensional.
Sclerotherapy spares ovarian reserve without loss of therapeutic efficacy
By Kate Madden Yee
The results offer evidence that supports sclerotherapy as an ovary-sparing alternative to surgery for selected patients.
March 25, 2026
Ovary
Technologist aides may support IR procedures amid staffing shortages
By Amerigo Allegretto
Radiologic technologist aides who were trained in sterile technique and ultrasound setup could support IR services.
March 25, 2026
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Can AI reduce malpractice risk for radiologists?
By Liz Carey
Radiologist takes proactive approach facing new era of AI-assisted medicine.
March 25, 2026
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Tailoring breast radiotherapy to women's risk leads to success
By Amerigo Allegretto
Many women don't have breast cancer recurrence after receiving radiotherapy following initial treatment, a study showed at EBCC15.
March 24, 2026
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Study finds that AI fails to speed lung cancer diagnosis
By Will Morton
AI prioritization of chest x-rays requested by U.K. primary care had no significant impact on the lung cancer pathway.
March 24, 2026
Lung Ai
Thermal ablation safe, effective for treating liver tumors
By Amerigo Allegretto
Percutaneous thermal ablation for treating liver tumors has a near-zero 90-day mortality rate and a low major complication rate.
March 24, 2026
Liver Cancer 400
Can you spot a ‘deepfake’ x-ray?
By Will Morton
Deepfake medical images often look too perfect.
March 24, 2026
Anatomy-matched real and GPT-4o-generated radiographs: (A) real and (B) GPT-4o-generated posteroanterior chest radiographs, (C) real and (D) GPT-4ogenerated lateral cervical spine radiographs, (E) real and (F) GPT-4o-generated posteroanterior hand radiographs, and (G) real and (H) GPT-4o-generated lateral lumbar spine radiographs. The pairs demonstrate that GPT-4o can produce radiographically plausible images across different anatomic regions.
9 medical societies advocate for updated fluoroscopy safety standards
By Kate Madden Yee
The new safety framework is called ALARA+, or "As Low and As Light as Reasonably Achievable."
March 24, 2026
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Podcast: Experts eye legal cues and clues in MRI safety failure
By Liz Carey
In describing a leaked video, Gilk and Posh point out the apparent safety errors.
March 24, 2026
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