ASTRO proposes new guidelines for aggressive breast cancer and DCIS

The American Society for Radiation Oncology (ASTRO) has released a proposed update to clinical practice guidelines for partial breast radiation as an alternative to whole breast radiation for early-stage invasive breast cancer and ductal carcinoma in situ (DCIS).

ASTRO’s recommendations are based on evidence from major clinical trials, said Janice Lyons, MD, chair of the guideline task force at the University Hospitals Seidman Cancer Center in Cleveland, OH, in a statement released by the society. The new guidance also addresses aspects related to the technical delivery of partial breast irradiation (PBI), including dose-fractionation regimens, target volumes, and treatment parameters for different PBI techniques.

In particular, the guideline was developed to clarify patient selection criteria and appropriate modalities for the delivery of PBI without whole breast irradiation, according to the related article published November 14 in Practical Radiation Oncology.

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