Monday, December 2 | 3:20 p.m.-3:30 p.m. | SSE02-03 | Room E451B
Do women with dense breast tissue who have a normal digital breast tomosynthesis (DBT) exam need supplemental whole-breast ultrasound (WBUS) imaging? Perhaps not, according to research to be presented Monday afternoon.Presenter Dr. Liane Philpotts of Yale University and colleagues conducted a study that explored the performance outcomes of supplemental handheld WBUS screening in women with dense tissue after a normal tomosynthesis screening mammogram. The study included 5,742 WBUS exams acquired between October 2017 and September 2018; the group tracked final BI-RADS assessments, lesion size and type, and outcome of BI-RADS 3 (probably benign) and 4 (suspicious) cases.
The majority of the WBUS exams' final BI-RADS assessments were 1 or 2 (97.2%); 2.4% were BI-RADS 3 and 0.4% were BI-RADS 4. Two cancer cases were identified, for a detection rate of 0.7 per 1,000 exams.
The findings raise the question of whether supplemental ultrasound after a normal DBT exam in women with dense tissue is needed, Philpotts and colleagues concluded.
"After normal tomosynthesis mammograms, the majority of WBUS cases were found to be normal, with only a small proportion of cases requiring follow-up or biopsy," they wrote in their abstract.












![A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/07/2026-07-14-radiology-mammogram-ai-auto-bias.H0bYO8QlWs.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)






