A coalition of Canadian breast cancer experts has published the country's first national consensus recommendations for breast cancer staging and treatment, covering all major breast cancer subtypes, in a suite of papers released in the journal Current Oncology.
The REAL Canadian Breast Cancer Alliance, established in 2023, developed the recommendations. The recommendations cover clinical breast cancer staging, HER2-positive breast cancer treatment, hormone receptor-positive early and advanced stage breast cancer management, and triple-negative breast cancer management.
The guidance integrates clinical data from major international conferences including the European Society for Medical Oncology (ESMO), the American Society of Clinical Oncology (ASCO), and the San Antonio Breast Cancer Symposium.
The recommendations are available open-access to clinicians, researchers, and policymakers at realalliance.ca.
![A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/07/2026-07-14-radiology-mammogram-ai-auto-bias.H0bYO8QlWs.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
