U.K. grants CapeRay patent for DBT with ABUS

AuntMinnie.com staff writers
Jun 11, 2020
2020 06 12 22 36 6634 Patented Stamp 400

South African mammography developer CapeRay Medical was awarded a U.K. patent (GB2566942) for technology that combines digital breast tomosynthesis (DBT) with automated breast ultrasound (ABUS).

The patent extends the company's intellectual property in the field of breast imaging by combining DBT and ABUS. Patients lie in a supine position and 3D images are acquired sequentially with the breasts in the same orientation and degree of compression under the influence of gravity.

The U.S. Patent and Trademark Office is reviewing the patent and CapeRay is taking advantage of the agency's Patent Prosecution Highway, which means much faster grant times and higher success rates.

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(A) Free-response receiver operating characteristic (FROC) curve for DBT-DINO and DINOv2 (Meta AI) on the detection task. DINOv2 achieved higher sensitivity than DBT-DINO across most false-positive thresholds. (B) Detection rates of DBT-DINO and DINOv2 for lesions that were ultimately found to be benign (n = 70) and lesions that were found to be cancerous (n = 66). Error bars represent 95% CIs estimated via patient-level bootstrapping with 1000 repetitions. Both models showed similar detection rates for cancerous lesions, whereas DINOv2 detected more benign lesions than DBT-DINO. (C) Example bounding box predictions for DBT-DINO and DINOv2 on the detection test set. Each image is a single two-dimensional section from a three-dimensional digital breast tomosynthesis volume; the first column shows a mediolateral oblique view, and the second and third columns show craniocaudal views. Both models struggled to detect very small lesions, such as the 3-mm-diameter lesion shown in the first column. FP = false positive.
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