
Sunday, December 1 | 11:15 a.m.-11:25 a.m. | SSA01-04 | Room S406A
An artificial intelligence (AI) algorithm can be used for standalone interpretation of mammograms that have a low probability of being malignant, researchers from the University of Southern California will report in this presentation.Studies have shown that the accuracy of AI-based algorithms for 2D mammography can match or exceed that of the average radiologist, presenter Dr. Alyssa Watanabe and colleagues noted. The group conducted a study to test this conclusion by evaluating the accuracy of an AI-based algorithm set to a 99% sensitivity threshold on a set of 1,255 screening mammograms.
The exams consisted of both benign and malignant cases. Out of the total pool of cases, the AI algorithm classified 40% as not suspicious; no cancers were found in the cases when the team compared them with biopsy and/or long-term follow-up data. In addition, the algorithm categorized 99% of biopsy-proven cancers as suspicious.
"Using a high sensitivity threshold, it is possible that AI-based software could potentially be used as a standalone to eliminate very low probability for malignancy cases from the radiologist worklist," Watanabe and colleagues concluded.
This paper received a Roadie 2019 award for the most popular abstract by page views in this Road to RSNA section.












![A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/07/2026-07-14-radiology-mammogram-ai-auto-bias.H0bYO8QlWs.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)






