Digitizer manufacturer Howtek of Hudson, NH, plans to expand its product line by merging with computer-aided detection (CAD) developer Intelligent Systems Software (ISSI) of Boca Raton, FL.
Howtek will exchange 8.4 million shares of common stock for all of ISSI’s outstanding stock. ISSI will be merged into a subsidiary of Howtek, and ISSI chairman, president, and CEO Kip Speyer will become Howtek’s chairman and CEO. Howtek president Scott Parr will continue in that position. Howtek and ISSI will continue to maintain their respective offices in New Hampshire and Florida.
The deal expands on an existing relationship between the firms, in which Howtek has been supplying its MultiRad digitizers to ISSI for use with that company’s MammoReader CAD system. MammoReader received FDA approval in January 2002. Howtek said it will continue to provide digitizers to ISSI and other OEM clients following completion of the merger, which is expected to occur by June 30.
By AuntMinnie.com staff writers
January 20, 2002
Related Reading
ISSI receives FDA approval, January 17, 2002
ISSI to use Howtek digitizers, November 19, 2001
Ferrania picks Howtek digitizers, November 12, 2001
Howtek's Q2 financials dip, August 7, 2001
Howtek debuts MyLivingRecord, May 25, 2001
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![A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/07/2026-07-14-radiology-mammogram-ai-auto-bias.H0bYO8QlWs.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)






