Cleveland Clinic develops breast shield

AuntMinnie.com staff writers

Aug 29, 2001

Radiologists at the Cleveland Clinic in Ohio have invented a shield designed to protect healthy breast tissue from radiotherapy scatter-related damage. A team of Cleveland Clinic radiation oncologists and physicists developed the first working model of the mobile breast shield in 1999. Subsequent clinical trials demonstrated the shield cut the radiation dose to healthy breasts up to 70%.

"Radiation risks to healthy breast tissue in radiotherapy treatment appear to be insignificant for a majority of women," said Dr. Roger Macklis, chairman of the department of radiation oncology at the Cleveland Clinic.

"The review of data on contralateral breast cancer risk, however, indicates there might be a small group of patients with known epidemiological risk factors who may be at increased risk of developing second breast cancers in the opposite breast," he added.

The breast shield technology is now available to all patients receiving radiotherapy for breast cancer at the Cleveland Clinic.

By AuntMinnie.com staff writers
August 30, 2001

Copyright © 2001 AuntMinnie.com

(A) Free-response receiver operating characteristic (FROC) curve for DBT-DINO and DINOv2 (Meta AI) on the detection task. DINOv2 achieved higher sensitivity than DBT-DINO across most false-positive thresholds. (B) Detection rates of DBT-DINO and DINOv2 for lesions that were ultimately found to be benign (n = 70) and lesions that were found to be cancerous (n = 66). Error bars represent 95% CIs estimated via patient-level bootstrapping with 1000 repetitions. Both models showed similar detection rates for cancerous lesions, whereas DINOv2 detected more benign lesions than DBT-DINO. (C) Example bounding box predictions for DBT-DINO and DINOv2 on the detection test set. Each image is a single two-dimensional section from a three-dimensional digital breast tomosynthesis volume; the first column shows a mediolateral oblique view, and the second and third columns show craniocaudal views. Both models struggled to detect very small lesions, such as the 3-mm-diameter lesion shown in the first column. FP = false positive.

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Images in a 70-year-old asymptomatic woman with a prior excisional biopsy in the left breast yielding lobular carcinoma in situ 3 years earlier. Screening contrast-enhanced mammography (CEM) was performed, which was considered a prevalence screen as the woman had no prior breast MRI in the past 3 years and no prior CEM. (A) Low-energy (26–30 kVp) mediolateral oblique (MLO) and (B) craniocaudal (CC) views show surgical clips but no abnormality. (C) Recombined MLO and (D) CC images show an enhancing mass in the medial left breast (arrows). Biopsy revealed invasive lobular carcinoma. Size was 0.2 cm; tumor grade II/III; negative lymph nodes; and estrogen receptor–positive, progesterone receptor–positive, and human epidermal growth factor receptor 2–negative.

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