The American Society of Nuclear Cardiology (ASNC) has released a new information statement with instructions for the safe and effective use of F-18 myocardial perfusion imaging (MPI) radiopharmaceuticals.
The new guidance covers important radiation, clinical, protocol, and interpretation information and follows the recent launch of F-18 flurpiridaz (Flyrcado, GE HealthCare) -- the first PET MPI tracer approved in the U.S. in 30 years. The guide also sets the stage for additional F-18 perfusion tracers currently in development. There are significant differences between these radioisotopes and the tracers imagers have been using, such as rubidium-82 and nitrogen-13 ammonia, the ASNC said in a statement.
The information statement was published recently in the Journal of Nuclear Cardiology and is intended for the entire nuclear cardiology team, the ASNC noted.



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![Comparative PET/CT scan images showing [18F]FAPI and [18F]FDG imaging with MIP projections, fusion views, and CT cross-sections for medical diagnosis](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/10/fapi-vs-fdg.nL6Acp6W2i.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)






