The U.S. Food and Drug Administration (FDA) has granted 510(k) clearance to Canon Medical Systems USA for use of its artificial intelligence-based Advanced Intelligent Clear-IQ Engine (AiCE) image reconstruction technology with its Aquilion Precision ultrahigh-resolution CT scanner.
Following previous FDA clearance for AiCE CT reconstruction software, the technology now has regulatory clearance for application to ultrahigh-resolution CT scans. Clinicians can thus use the deep convolutional neural network image reconstruction technology of AiCE to roughly double the spatial resolution of conventional CT scans at equivalent radiation doses, according to the company.
AiCE is capable of suppressing image noise while enhancing signal three to five times more quickly than traditional model-based iterative reconstruction (MBIR) methods, Canon said.
![Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/06/hanneman.r6SMLzkezo.png?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
