Inhale > Silicosis

Chest 1992 Feb;101(2):366-370. Acute silicosis responding to corticosteroid therapy.

Goodman GB, Kaplan PD, Stachura I, Castranova V, Pailes WH, Lapp NL

The course of acute silicosis usually is relentlessly progressive. Death results from cor pulmonale and respiratory failure, with mycobacterial infection a frequent serious complication. Attempts to treat the illness generally have been unavailing. We report an unusual case of acute silicosis in which improvement in clinical status, chest x-ray film findings and pulmonary function occurred following therapy with corticosteroids. To our knowledge, this is the first such case reported in the medical literature.

PMID: 1735256, MUID: 92136885

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