Brianna Knowles and Russ Knowles

Nov 26, 2012
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County-level net change in radiation oncology practice sites from first appearance through 2025.
ASTRO highlights study on disappearing radiation oncology centers
July 10, 2026
Ctca
CCTA finds coronary disease in men with erectile dysfunction
July 10, 2026
Marijuana
Marijuana use linked to greater coronary plaque burden
July 10, 2026
MRI false positive for additional disease, (top to bottom): A. Index lesion—grade 2 invasive ductal carcinoma; B. MRI lesion two, upper inner quadrant: Stromal sclerosis and columnar cell change; C. MRI lesion three, upper outer quadrant: No ultrasound correlate, no malignancy on follow-up; D. CEM marked background parenchymal enhancement with a unifocal retroareolar lesion demonstrating wash-out on delayed MLO. Images are republished under a Creative Commons license (CC BY 4.0).
CEM on par with MRI for breast cancer diagnosis, local staging
July 10, 2026
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ASTRO highlights study on disappearing radiation oncology centers
By Amerigo Allegretto
Over two-thirds of all U.S. counties reported lacking a radiation oncology practice site in 2025.
July 10, 2026
County-level net change in radiation oncology practice sites from first appearance through 2025.
CCTA finds coronary disease in men with erectile dysfunction
By Will Morton
Erectile dysfunction caused by vascular problems is associated with a higher risk of coronary artery disease.
July 10, 2026
Ctca
Marijuana use linked to greater coronary plaque burden
By Will Morton
Marijuana users demonstrated more than double coronary artery calcium scores than nonusers.
July 10, 2026
Marijuana
CEM on par with MRI for breast cancer diagnosis, local staging
By Amerigo Allegretto
CEM alone in a prospective study achieved perfect sensitivity and negative predictive value in diagnosing breast cancer.
July 10, 2026
MRI false positive for additional disease, (top to bottom): A. Index lesion—grade 2 invasive ductal carcinoma; B. MRI lesion two, upper inner quadrant: Stromal sclerosis and columnar cell change; C. MRI lesion three, upper outer quadrant: No ultrasound correlate, no malignancy on follow-up; D. CEM marked background parenchymal enhancement with a unifocal retroareolar lesion demonstrating wash-out on delayed MLO. Images are republished under a Creative Commons license (CC BY 4.0).
Ultrasound MinnieCast, Episode 12: AI adds to ultrasound in global maternity care
By Amerigo Allegretto
Researchers from Google Research share results of a study on an AI ultrasound model estimating gestational age in pregnant women.
July 10, 2026
Minnie Cast Thumbnail (14)
New PET tracer show promise in neuroblastoma
By Will Morton
F-18 mFBG achieved a pooled sensitivity of 97%, compared with 82% for I-123 MIBG.
July 9, 2026
Cancer Target
AI ultrasound model accurately estimates gestational age
By Amerigo Allegretto
The model achieved noninferiority compared to standard clinical assessments in healthcare settings based in the U.S. and Africa.
July 9, 2026
Ultrasound In Africa 400
AR-guided localization may sub for CT for early-stage lung cancer
By Amerigo Allegretto
AR-guided localization was noninferior to conventional CT guidance and led to better patient experiences.
July 8, 2026
Lungs 3 D Research 400
Study backs LDCT lung cancer screening in Singapore
By Will Morton
Lung cancer is the leading cause of cancer death in Singapore, with approximately 48% of cases occurring in individuals who have never smoked.
July 8, 2026
Lungs
New criteria evaluates treatment response in bone metastases
By Will Morton
RECIBM-defined response classifications showed high agreement with established criteria and reclassified 19% of patients.
July 7, 2026
Response Evaluation Criteria in Bone Metastases (RECIBM) and metabolic criteria were used to detect a complete response missed at anatomic assessment. A 76-year-old male patient presented with 1 month of hemoptysis and was diagnosed with small cell lung cancer and bone metastases. Baseline (July 2022) F-18 FDG-PET/CT images (A, maximum intensity projection image; B–E, axial images) demonstrate FDG-avid lesions in the left lamina of the first lumbar vertebra (L1) (straight yellow arrows; maximum standardized uptake value, 2.74; peak standardized uptake value normalized to lean body mass, 1.59) and left ilium (curved yellow arrows; maximum standardized uptake value, 3.68; peak standardized uptake value normalized to lean body mass, 2.28). After seven chemotherapy cycles (December 2022), follow-up PET/CT images (F, maximum intensity projection image; G–J, axial images) show complete metabolic resolution of bony lesions (L1: maximum standardized uptake value, 1.32, and peak standardized uptake value normalized to lean body mass, 0.85; left ilium: maximum standardized uptake value, 1.48, and peak standardized uptake value normalized to lean body mass, 0.82), without apparent osteolytic or osteoblastic changes at CT. Assessment was stable disease (SD) according to the University of Texas MD Anderson Cancer Center (MDA) criteria but complete response (CR) or complete metabolic response (CMR) according to RECIBM, PET Response Criteria in Solid Tumors (PERCIST), and European Organization for Research and Treatment of Cancer (EORTC) criteria. The patient was alive as of September 30, 2025.
CT sign may flag who benefits from subdural hematoma procedure
By Will Morton
Among participants with the “the hyperdense capsule sign,” middle meningeal artery embolization resulted in significant benefits over usual care.
July 7, 2026
Representative axial noncontrast CT images with and without the hyperdense capsule sign (HDCS). The HDCS is defined as a hyperdense capsule layer of linear shape surrounding a subdural hematoma (SDH). (A–D) Images of SDH with the HDCS (arrowheads). (E–H) Images of SDH without the HDCS.
Classification system could improve MRI lumbar spinal stenosis grading
By Amerigo Allegretto
An educational intervention that use a classification system led to improved overall correctness and interobserver reliability.
July 6, 2026
Spine 400
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