Confirma inks research deal with UCSD

AuntMinnie.com staff writers

Apr 2, 2003

Image-processing firm Confirma and the Robert M. Berk Magnetic Resonance Institute at the University of California, San Diego have signed an agreement to conduct research using Confirma’s CADstream system for breast MR image processing and analysis.

Researchers plan on evaluating the product for breast MR image processing and its impact on breast MRI interpretation. The first study will focus on measuring the effect of the system’s processing on reader sensitivity and specificity -- two important criteria in measuring the efficacy of MRI, according to the Kirkland, WA-based company.

By AuntMinnie.com staff writers
April 3, 2003
Related Reading

Lyon tapped as president, CEO of Confirma, March 27, 2003

Confirma partners with Sectra, March 18, 2003

Confirma to launch breast MRI CAD software, November 25, 2002

Copyright © 2003 AuntMinnie.com

(A) Free-response receiver operating characteristic (FROC) curve for DBT-DINO and DINOv2 (Meta AI) on the detection task. DINOv2 achieved higher sensitivity than DBT-DINO across most false-positive thresholds. (B) Detection rates of DBT-DINO and DINOv2 for lesions that were ultimately found to be benign (n = 70) and lesions that were found to be cancerous (n = 66). Error bars represent 95% CIs estimated via patient-level bootstrapping with 1000 repetitions. Both models showed similar detection rates for cancerous lesions, whereas DINOv2 detected more benign lesions than DBT-DINO. (C) Example bounding box predictions for DBT-DINO and DINOv2 on the detection test set. Each image is a single two-dimensional section from a three-dimensional digital breast tomosynthesis volume; the first column shows a mediolateral oblique view, and the second and third columns show craniocaudal views. Both models struggled to detect very small lesions, such as the 3-mm-diameter lesion shown in the first column. FP = false positive.

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Images in a 70-year-old asymptomatic woman with a prior excisional biopsy in the left breast yielding lobular carcinoma in situ 3 years earlier. Screening contrast-enhanced mammography (CEM) was performed, which was considered a prevalence screen as the woman had no prior breast MRI in the past 3 years and no prior CEM. (A) Low-energy (26–30 kVp) mediolateral oblique (MLO) and (B) craniocaudal (CC) views show surgical clips but no abnormality. (C) Recombined MLO and (D) CC images show an enhancing mass in the medial left breast (arrows). Biopsy revealed invasive lobular carcinoma. Size was 0.2 cm; tumor grade II/III; negative lymph nodes; and estrogen receptor–positive, progesterone receptor–positive, and human epidermal growth factor receptor 2–negative.

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