
An artificial intelligence (AI) neural network used with lung CT scans can help clinicians assess cancer severity and develop treatment options, according to research conducted by a team from Stanford University.
A group led by Olivier Gevaert, PhD, created a neural network called LungNet to gather lung cancer information from CT scans, particularly those from adults with non-small cell lung cancer (NSCLC), which represents the majority of diagnoses of the disease.
The group trained the network on four patient cohorts with NSCLC from four medical centers. LungNet accurately predicted overall survival in all four patient groups, accurately categorized benign and malignant nodules, and it further classified nodules according to cancer progression, according to the researchers.
"LungNet demonstrates the benefits of designing and training machine learning tools directly on medical images from patients," contributing author Qi Duan, PhD, said in a statement released on June 24 by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), which funded the research. "This is an outstanding example of how machine-learning technology can be a cost-effective approach to advance disease detection, diagnosis, and treatment."
















![Images show the pectoralis muscles of a healthy male individual who never smoked (age, 66 years; height, 178 cm; body mass index [BMI, calculated as weight in kilograms divided by height in meters squared], 28.4; number of cigarette pack-years, 0; forced expiratory volume in 1 second [FEV1], 97.6% predicted; FEV1: forced vital capacity [FVC] ratio, 0.71; pectoralis muscle area [PMA], 59.4 cm2; pectoralis muscle volume [PMV], 764 cm3) and a male individual with a smoking history and chronic obstructive pulmonary disorder (COPD) (age, 66 years; height, 178 cm; BMI, 27.5; number of cigarette pack-years, 43.2, FEV1, 48% predicted; FEV1:FVC, 0.56; PMA, 35 cm2; PMV, 480.8 cm3) from the Canadian Cohort Obstructive Lung Disease (i.e., CanCOLD) study. The CT image is shown in the axial plane. The PMV is automatically extracted using the developed deep learning model and overlayed onto the lungs for visual clarity.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/03/genkin.25LqljVF0y.jpg?auto=format%2Ccompress&crop=focalpoint&fit=crop&h=112&q=70&w=112)



