Sunday, November 25 | 11:05 a.m.-11:15 a.m. | SSA03-03 | Room S404AB
CT myocardial perfusion may be a better predictor for major adverse cardiac events in patients with coronary artery disease than fractional flow reserve CT (FFR-CT), according to this study being presented on Sunday.Researchers from the Medical University of South Carolina and the University of Groningen in the Netherlands reviewed the imaging data of 81 patients with coronary artery disease (CAD) who underwent both coronary CT angiography (CCTA) and stress dynamic CT myocardial perfusion at one of four institutions. They used FFR-CT and myocardial blood-flow measurements from these data to estimate the prognostic value of the two imaging modalities.
Both FFR-CT and CT perfusion had a higher area under the curve for predicting major adverse cardiac events, with blood-flow measurements from CT perfusion providing the most accurate predictions. Combining the information from the two techniques further improved their predictive value, compared with using either of the techniques alone.
"Dynamic CT perfusion has the highest predictive value for major adverse cardiac events," doctoral candidate Marly van Assen told AuntMinnie.com. "Both FFR-CT and CT perfusion have added value in the prognostication of major adverse cardiac events and could provide complementary information."
![Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/06/hanneman.r6SMLzkezo.png?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
