Picture Health has published results of a multicenter study evaluating its quantitative vessel tortuosity (QVT) score AI imaging biomarker for predicting immunotherapy outcomes in non-small cell lung cancer (NSCLC).
The study, published in the Journal for ImmunoTherapy of Cancer, evaluated more than 1,300 CT scans from 682 patients treated at six medical centers.
Researchers found that QVT scores at the start of treatment independently predicted survival outcomes, and that early decreases in QVT scores during treatment appeared sooner than traditional tumor response measures, Picture Health said.
The QVT score analyzes the structure and complexity of tumor blood vessel networks using more than 900 measurements derived from routine CT scans to detect early signs of treatment response and predict outcome, according to Picture Health.
The study findings may be read on the journal’s website.
![Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/06/hanneman.r6SMLzkezo.png?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
