Inflammatory Myofibroblastic tumor:
Clinical:
Inflammatory myofibroblastic tumor (IMT) is a rare benign lesion composed of spindle-cell proliferation and inflammatory components [1]. IMT is the most common primary mass of the lung in children, accounting for 16-38% of primary lung tumors [1]. Children present with cough, fever, chest pain, and hemoptysis [1].The biologic behavior is intermediate, with potential for local recurrence and rare distant metastases (fewer than 2% of cases) [1]. Molecular rearrangements of the anaplastic lymphoma kinase locus on chromosome 2p23 manifest in 50% or more of cases of IMT, but this may be less true in cases of pulmonary IMT [1].
Treatment is surgical resection and this is curative in most cases [1].
X-ray:
Characteristically, the lesion appears as a peripheral lobulated mass with a lower-lobe predominance [1]. Calcification occurs in about 15% of cases, and is more commonly seen in children than adults [1].
A notible feature is hyperintensity on T2 MR imaging due to the presence of mxyoid stroma in the tumor [1].
REFERENCES:
(1) Radiographics 2018; Lichtenberger JP, et al. Primary lung tumors in children: radiologic-pathologic correlation. 38: 2151-2172
