Duke University Cardiovascular MR Practicum

Sep 27th, 2015Oct 1st, 2015

Durham, NC

US

http://pub.lucidpress.com/DCMRC_fall_course/

Phone:919-668-1671

This practicum, developed by the Duke Cardiovascular MR Center, is designed to provide the participant with the principles of CMR imaging and protocols currently available to evaluate the structure and function of the cardiovascular system.

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The patient was a woman in her 50s with suspected recurrence of invasive lobular breast cancer. A, maximum intensity projection image from FDG-PET/CT demonstrating avid foci in the chest (red arrow). Transaxial CT (B) and transaxial fused FDG-PET/CT image (C) showing that the chest avidity corresponds to FDG-avid lung nodules (red arrows) suspicious for malignancy. The lung nodule was subsequently biopsied but found to represent benign granulomatous inflammation and thus a false positive on FDG-PET/CT. D, maximum intensity projection image from FES-PET/CT demonstrating multifocal uptake suspicious for malignancy. E, transaxial CT and fused FES-PET/CT demonstrating no FES-avidity in the biopsy proven benign granulomatous lung nodules (red arrows), thus true negative on FES-PET/CT. FES-avidity in nodes (white arrow) is suspicious for malignancy. F, transaxial CT and fused FES-PET/CT demonstrates gastric avidity (blue arrow) suspicious for malignancy. G, transaxial CT and fused FES PET/CT demonstrates FES-avid osseous foci (yellow arrow) suspicious for malignancy. This osseous focus was subsequently biopsied and proved to be an osseous metastasis and thus true positive on FES-PET/CT.

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CT images from a 24-year-old woman with history of ventriculopleural shunt placement who presented with chest pain show two small linear hyperattenuating structures (A, arrows), with larger hyperattenuating structure oriented parallel and very close to the rib. The AI algorithm interpreted the finding as a rib fracture. (B) An additional axial image from same exam indicates that the finding relates to the patient’s ventriculopleural shunt (arrow), passing alongside the rib. The radiologist made a correct interpretation upon assessment of the entire exam. Image courtesy of the ARRS.

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Coronal and axial slice of the average cortical F-18 MK-6240 SUVR [standard uptake value ratio] image for each study population. SUVR images were corrected for partial volume effects and masked with the gray matter mask used for volume of interest delineation. Overall tau accumulation is comparable between the late-life depression (LLD, middle column) and non-depressed cognitively unimpaired comparison (HC, left column) groups, while abnormal tau accumulation, which is most pronounced in the mesial temporal lobe, can be seen in the mild cognitive impairment due to Alzheimer's disease group (right column). Image and caption courtesy of the American Journal of Geriatric Psychiatry.

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Example of the flortaucipir tau-PET signal and distribution of low grey matter volume in a single former athlete. Spatial maps of the flortaucipir tau-PET standardized update value (SUVR) (top) and the reduced grey matter volumes showed in blue and defined as voxels with a w-score of >1.5 below the mean (bottom) in a single former athlete. Image courtesy of the Journal of Neurology.

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Imaging in a 56-year-old woman with heterogeneously dense breasts (BIRADS C). (A) Left craniocaudal (left) and mediolateral oblique (right) digital mammograms show no abnormality. (B) Left craniocaudal (LCC, top) and left mediolateral oblique (LMLO, bottom) mammograms with retrospectively applied AI (Lunit Insight MMG, version 1.1.7.1; Lunit) show the lesion was given abnormality scores of 97% and 71%, respectively. The color bar indicates pixel-level abnormality scores corresponding to heatmap contour lines. Breast ultrasound performed the same day was considered negative (not shown). (C) Left craniocaudal (left) and mediolateral oblique (right) digital mammograms acquired nine months later show an irregular mass (arrows) in the left breast, which correlates with the heatmap areas scored as 97% and 71% by AI in the earlier screening mammogram (B). The radiopaque round marker denotes the site of the palpable abnormality indicated by the patient. (D) Transverse ultrasound imaging shows an irregular mass (arrow) in the left breast. The patient was treated with breast-conserving surgery, and the mass was proven to be invasive lobular carcinoma. Image courtesy of the RSNA.

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