Dr. Gregory Sorensen

Nuclear Medicine
Alzheimer's disease: Reason for hope
When President Reagan welcomed women's basketball coach Pat Summitt to the White House 25 years ago, no one knew that Alzheimer's would someday become a thread connecting them. Fortunately, imaging now offers more certainty for those who may unknowingly have the disease, according to Siemens Healthcare CEO Dr. Gregory Sorensen.
August 5, 2012
2012 08 03 13 29 17 498 Sorensen Gregory 70
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AR-guided localization may sub for CT for early-stage lung cancer
AR-guided localization was noninferior to conventional CT guidance and led to better patient experiences.
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Study backs LDCT lung cancer screening in Singapore
Response Evaluation Criteria in Bone Metastases (RECIBM) and metabolic criteria were used to detect a complete response missed at anatomic assessment. A 76-year-old male patient presented with 1 month of hemoptysis and was diagnosed with small cell lung cancer and bone metastases. Baseline (July 2022) F-18 FDG-PET/CT images (A, maximum intensity projection image; B–E, axial images) demonstrate FDG-avid lesions in the left lamina of the first lumbar vertebra (L1) (straight yellow arrows; maximum standardized uptake value, 2.74; peak standardized uptake value normalized to lean body mass, 1.59) and left ilium (curved yellow arrows; maximum standardized uptake value, 3.68; peak standardized uptake value normalized to lean body mass, 2.28). After seven chemotherapy cycles (December 2022), follow-up PET/CT images (F, maximum intensity projection image; G–J, axial images) show complete metabolic resolution of bony lesions (L1: maximum standardized uptake value, 1.32, and peak standardized uptake value normalized to lean body mass, 0.85; left ilium: maximum standardized uptake value, 1.48, and peak standardized uptake value normalized to lean body mass, 0.82), without apparent osteolytic or osteoblastic changes at CT. Assessment was stable disease (SD) according to the University of Texas MD Anderson Cancer Center (MDA) criteria but complete response (CR) or complete metabolic response (CMR) according to RECIBM, PET Response Criteria in Solid Tumors (PERCIST), and European Organization for Research and Treatment of Cancer (EORTC) criteria. The patient was alive as of September 30, 2025.
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New criteria evaluates treatment response in bone metastases
Representative axial noncontrast CT images with and without the hyperdense capsule sign (HDCS). The HDCS is defined as a hyperdense capsule layer of linear shape surrounding a subdural hematoma (SDH). (A–D) Images of SDH with the HDCS (arrowheads). (E–H) Images of SDH without the HDCS.
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AR-guided localization may sub for CT for early-stage lung cancer
By Amerigo Allegretto
AR-guided localization was noninferior to conventional CT guidance and led to better patient experiences.
July 8, 2026
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Study backs LDCT lung cancer screening in Singapore
By Will Morton
Lung cancer is the leading cause of cancer death in Singapore, with approximately 48% of cases occurring in individuals who have never smoked.
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New criteria evaluates treatment response in bone metastases
By Will Morton
RECIBM-defined response classifications showed high agreement with established criteria and reclassified 19% of patients.
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Response Evaluation Criteria in Bone Metastases (RECIBM) and metabolic criteria were used to detect a complete response missed at anatomic assessment. A 76-year-old male patient presented with 1 month of hemoptysis and was diagnosed with small cell lung cancer and bone metastases. Baseline (July 2022) F-18 FDG-PET/CT images (A, maximum intensity projection image; B–E, axial images) demonstrate FDG-avid lesions in the left lamina of the first lumbar vertebra (L1) (straight yellow arrows; maximum standardized uptake value, 2.74; peak standardized uptake value normalized to lean body mass, 1.59) and left ilium (curved yellow arrows; maximum standardized uptake value, 3.68; peak standardized uptake value normalized to lean body mass, 2.28). After seven chemotherapy cycles (December 2022), follow-up PET/CT images (F, maximum intensity projection image; G–J, axial images) show complete metabolic resolution of bony lesions (L1: maximum standardized uptake value, 1.32, and peak standardized uptake value normalized to lean body mass, 0.85; left ilium: maximum standardized uptake value, 1.48, and peak standardized uptake value normalized to lean body mass, 0.82), without apparent osteolytic or osteoblastic changes at CT. Assessment was stable disease (SD) according to the University of Texas MD Anderson Cancer Center (MDA) criteria but complete response (CR) or complete metabolic response (CMR) according to RECIBM, PET Response Criteria in Solid Tumors (PERCIST), and European Organization for Research and Treatment of Cancer (EORTC) criteria. The patient was alive as of September 30, 2025.
CT sign may flag who benefits from subdural hematoma procedure
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Among participants with the “the hyperdense capsule sign,” middle meningeal artery embolization resulted in significant benefits over usual care.
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Representative axial noncontrast CT images with and without the hyperdense capsule sign (HDCS). The HDCS is defined as a hyperdense capsule layer of linear shape surrounding a subdural hematoma (SDH). (A–D) Images of SDH with the HDCS (arrowheads). (E–H) Images of SDH without the HDCS.
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The findings underscore how environmental and social conditions work together to influence long-term bone health.
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More plans require cost-sharing for advanced imaging, with a growing share of plans requiring both coinsurance and a copayment.
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PET/CT guides treatment in men with recurrent prostate cancer
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F-18 fluciclovine and Ga-68 PSMA-11 PET/CT have similar benefits for sRT planning, in terms of improving cancer control without increased toxicity.
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F-18 fluciclovine PET/CT images in a 59-year-old man with biochemical recurrence after prostatectomy (prostate-specific antigen level, 0.42 ng/mL; Gleason score, 5 + 4 = 9; T3BN1M0). (A) Coronal PET and (B) maximum intensity projection images show multiple retroperitoneal lymph nodes with abnormal radiotracer uptake (arrows). (C) Axial PET and (D) axial fused PET/CT images show the index lesion (arrow), measuring 13 × 10 mm, on the right precaval lymph node. The initial decision to offer radiation therapy to the prostate bed and pelvis was changed to a decision not to offer radiation therapy.
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