Dr. Gregory Sorensen

Nuclear Medicine
Alzheimer's disease: Reason for hope
When President Reagan welcomed women's basketball coach Pat Summitt to the White House 25 years ago, no one knew that Alzheimer's would someday become a thread connecting them. Fortunately, imaging now offers more certainty for those who may unknowingly have the disease, according to Siemens Healthcare CEO Dr. Gregory Sorensen.
August 5, 2012
2012 08 03 13 29 17 498 Sorensen Gregory 70
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(A) Free-response receiver operating characteristic (FROC) curve for DBT-DINO and DINOv2 (Meta AI) on the detection task. DINOv2 achieved higher sensitivity than DBT-DINO across most false-positive thresholds. (B) Detection rates of DBT-DINO and DINOv2 for lesions that were ultimately found to be benign (n = 70) and lesions that were found to be cancerous (n = 66). Error bars represent 95% CIs estimated via patient-level bootstrapping with 1000 repetitions. Both models showed similar detection rates for cancerous lesions, whereas DINOv2 detected more benign lesions than DBT-DINO. (C) Example bounding box predictions for DBT-DINO and DINOv2 on the detection test set. Each image is a single two-dimensional section from a three-dimensional digital breast tomosynthesis volume; the first column shows a mediolateral oblique view, and the second and third columns show craniocaudal views. Both models struggled to detect very small lesions, such as the 3-mm-diameter lesion shown in the first column. FP = false positive.
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