Will Morton

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AI helps predict kidney function decline in Lu-177 patients

An open-source AI tool can help predict renal function decline in prostate cancer patients undergoing lutetium-177 (Lu-177) radiopharmaceutical therapy.

February 25, 2025

An axial CT image illustrating segmentation of functioning kidney tissue (blue areas), excluding kidney cysts and renal pelvis, using TotalSegmentator. Image and caption courtesy of RSNA.

Molecular Imaging

PET/CT predicts relapse in patients with ovarian cancer

Pretreatment F-18 FDG-PET/CT scans may predict relapse in patients with advanced high-grade serous ovarian cancer.

February 24, 2025

Ovarian Cancer Thumbnail

Molecular Imaging

PET/CT reveals new infections in ICU patients

F-18 FDG-PET/CT is a valuable approach for diagnosing unknown infections in intensive care unit (ICU) patients.

February 21, 2025

There are several conceivable advantages of F-18 FDG PET/CT over conventional imaging. Image A and B showing an example of the distinctive capability of the F-18 FDG PET/CT. A shows a fusion image of F-18 FDG PET/CT and low-dose CT and B an high resolution chest CT of a patient with an Aspergillus infection. The suspected aspergilloma is concealed on the high resolution CT due to the lung fluids and consolidation. Image C and D (fusion image of F-18 FDG PET/CT and low-dose CT and low-dose CT only, respectively) are examples of the ability to image inflammation while no concurrent abnormalities are visualized, in this case prostatitis (red arrows). Image E, a maximized intensity projection of F-18 FDG PET, shows a patient with lung infections and multiple muscle abscesses after MRSA sepsis. This is an illustrative example of a relevant dissemination investigation. Image and caption available for republishing under Creative Commons license (CC BY 4.0 DEED, Attribution 4.0 International) and courtesy of Annals of Intensive Care.

Molecular Imaging

New PET tracer developed for breast cancer

A new PET radiotracer shows promise for diagnosing triple-negative breast cancer.

February 14, 2025

Ga-68 FZ-NR-1 PET/CT images and F-18 FDG PET/CT and PET/MRI images in representative nectin-4-positive TNBC patients. (A) PET/CT images and nectin-4 immunohistochemistry (IHC) staining of patient 1. Maximum-intensity projection (MIP) images and axial and coronal PET/CT images of Ga-68 FZ-NR-1 and F-18 FDG both showed high uptake in lung metastases (arrow). (B) PET/CT images and nectin-4 IHC staining of patient 2. MIP images and axial and coronal PET/CT images of Ga-68 FZ-NR-1 showed high uptake in recurrence of right breast cancer after surgery (arrow), and those of F-18 FDG PET/MRI showed high uptake. Image courtesy of the Journal of Nuclear Medicine.

Molecular Imaging

Pluvicto safe in patients with impaired kidneys

Lu-177 prostate-specific membrane antigen-617 (Lu-177 PSMA-617, Pluvicto) may be safely delivered in patients with impaired renal function.

February 13, 2025

AI model annotates pediatric AXR reports

A large language model called Axpert demonstrates potential for automatically labeling necrotizing enterocolitis on infant abdominal x-ray (AXR) reports.

February 12, 2025

MRI model predicts pathologic features of liver cancer

A new scoring model for MRI exams shows potential for improving the assessment of early recurrence in patients with hepatocellular carcinoma.

February 11, 2025

2025 02 11 I Score Thumbnail

X-ray study reveals ‘smoking paradox’ in psoriatic arthritis patients

Current or past smoking does not appear to be significantly associated with radiographic progression in patients with psoriatic arthritis.

February 7, 2025

AI model detects low BMD on ankle and foot x-rays

An AI model that detects low bone mineral density (BMD) on ankle and foot x-rays could be useful for screening for osteoporosis.

February 6, 2025

2025 02 06 Ankle Osteoporosis

Molecular Imaging

Dosimetry key in Lu-177 cancer therapy

Personalized medicine is rapidly evolving in cancer theranostics, with technology now available that allows clinicians to optimize doses of radiopharmaceuticals on an individual patient level, according to experts.

February 5, 2025

Kesner Zanzonico

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Toe Joint

New procedure treats chronic pain in toe joints

Median pain scores dropped for 27 patients from nine to one after five months.

Health Disparities Label Adobe Eco Lens

HPI study, online tool identify and predict cancer disparities

$This image depicts comminuted skull fractures sustained in a pedestrian motor vehicle accident. These are difficult to document by a standard autopsy because the individual fragments are displaced during the internal examination and dissection of the head.$

Radiology CSI: CT helps medical examiners determine cause of death

Lung Cancer

Radiomics plus DL improve prediction of lung cancer invasiveness

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ASTRO: Low-dose RT effective for treating knee osteoarthritis

By Amerigo Allegretto

Research presented at ASTRO 2025 showed the effectiveness of low-dose radiation therapy for treating knee osteoarthritis.

September 29, 2025

Moscone Center Astro

ASTRO: Genomic test predicts benefit of hormone therapy in prostate cancer

Patients with a prostate tumor subtype known as luminal B had meaningful benefits from the addition of apalutamide to secondary radiotherapy.

September 29, 2025

Moscone Center Astro

ASTRO: Patient navigation key to mitigating RT treatment disparities

By Kate Madden Yee

"Patients are lost and need to be navigated," said presenter Christina Chapman, MD, of Baylor College of Medicine in Houston.

September 29, 2025

Moscone Center Astro

ASTRO: Radiotherapy offers opportunities beyond cancer treatment

By Kate Madden Yee

Radiotherapy isn't just for cancer treatment, according to talks at ASTRO 2025 in San Francisco.

September 28, 2025

Moscone Center Astro

Case report: Pluvicto as a first-line treatment in late-stage prostate cancer

Since 1996, the patient continually declined androgen deprivation therapy, chemotherapy, and local therapy to the prostate gland.

September 26, 2025

Burden of PSMA-expressing prostate cancer before and after treatment with two cycles of Lu-177 PSMA-617. (A and B) Reduction in overall disease burden is evident after treatment. Avidity of patient’s primary prostate tumor and his osseous metastasis shown before (C) and after (D) treatment.

New brain MRI technique could help identify Alzheimer's

By Kate Madden Yee

Researchers used 7-tesla MRI to demonstrate how microvessel pulses in the brain's deep white matter increase with age.

September 26, 2025

Scholarly activity low among residency program directors

By Amerigo Allegretto

Study results point toward program directors focusing on administrative responsibilities rather than scholarly activity.

September 26, 2025

Research Highlighter Res

3D DEXA shows value in patients with prostate cancer

3D DEXA may be a practical and valuable tool for detecting structural bone changes in prostate cancer patients.

September 25, 2025

Smith-Bindman unpacks NEJM pediatric CT study

By Kate Madden Yee

In a video interview, the researcher acknowledged CT's importance to patient care but advocated for its appropriate use.

September 25, 2025

Rebecca Smith-Bindman, MD

Women who skip first mammogram more likely to die of breast cancer

By Amerigo Allegretto

Women who do not participate in their first breast cancer screening are 40% more likely to die later from the disease.

September 24, 2025

Mammography Breast Ipad Patient 400

Study finds AI not cost-effective for breast cancer screening

By Amerigo Allegretto

AI is not cost-effective for breast cancer screening, even with reductions in mortality, false-positive cases, and false-negative cases, according to new research.

September 24, 2025

Breast Tomosynthesis Digital 400 (1)

ACS: Cancer survival rates are lower in rural areas

By Kate Madden Yee

The research also reported lower cancer survival rates for Blacks compared to whites, underscoring "disparities in receipt of care."

September 24, 2025

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