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Nov 26, 2014
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PET brain scans from the same individual with early signs of Alzheimer’s disease comparing two tau radiotracers: flortaucipir, shown at top, and the investigational tracer MK6240, shown at bottom. Areas of pathological tau accumulation appear in red. The MK6240 scan shows more extensive tau buildup, suggesting that this tracer may detect Alzheimer’s-related brain changes that are less visible with the standard tracer.
New tau PET tracer outperforms standard agent in Alzheimer’s disease
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New tau PET tracer outperforms standard agent in Alzheimer’s disease
By Will Morton
The findings are from a head-to-head comparison between F-18 MK-6240 and F-18 flortaucipir among 682 participants.
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PET brain scans from the same individual with early signs of Alzheimer’s disease comparing two tau radiotracers: flortaucipir, shown at top, and the investigational tracer MK6240, shown at bottom. Areas of pathological tau accumulation appear in red. The MK6240 scan shows more extensive tau buildup, suggesting that this tracer may detect Alzheimer’s-related brain changes that are less visible with the standard tracer.
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Maria Stanczak from ICUS shares her thoughts on recently proposed educational standards for CEUS training.
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Odds of amyloid positivity were 28% lower among Black people and 22% lower among Hispanic people.
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Bar graphs show mean success (blue) and confidence (orange) according to diagnostic response (lesion present or absent, shown as “present” and “absent,” respectively) and next-step decision (submit, additional tests, and consult a senior) for each group (radiologists and nonradiologists). Error bars indicate standard errors of the mean. Lesion-absent diagnoses were more prone to error and overconfidence than were lesion-present diagnoses.
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