Wednesday, November 28 | 5:00 p.m.-5:30 p.m. | LL-BRS-WE5C | Lakeside Learning Center
Adding digital breast tomosynthesis (DBT) to full-field digital mammography (FFDM) saves more than $10,000 per 1,000 women screened due to decreased recall rates, Yale University researchers have found.Dr. Vivek Kalra and colleagues explored the cost-effectiveness of breast screening using combined DBT and FFDM compared to FFDM alone, based on direct costs resulting from differences in the recall rate. The team calculated screening recall rates for combined DBT/FFDM studies and FFDM alone for a five-month period, then assessed the direct costs of these studies using regional Medicare reimbursement data. The study did not consider downstream direct costs, indirect costs, and intangible costs.
The group included data from 5,780 patients, 1,602 of whom had combined DBT/FFDM screening mammograms and 4,178 of whom had FFDM alone. The combined DBT/FFDM group had an overall recall rate of 7%, while the FFDM group had a recall rate of 10.9%. In addition, combined DBT/FFDM exams had a better cancer detection rate than FFDM alone, at 5.6 per 1,000 women, compared with 3.4 per 1,000 women.
Because combining DBT with FFDM reduces recall rates and improves cancer detection, Kalra's group concluded that it is preferable to FFDM alone for screening mammography.










![A normal mammogram confirmed by three-year radiologic follow-up illustrates reader-marked regions of interest (ROIs) during (A) unaided (round 1) and (B) artificial intelligence (AI)–assisted (round 2) reading. Each colored dot represents an ROI for recall by a human reader. Readers could mark more than one ROI per case, represented by multiple dots of the same color. During AI-assisted reading, the AI system displayed three visible prompts: two with suspicion of malignancy scores of 35% (left mediolateral oblique [L MLO] and craniocaudal [L CC]) and one with a suspicion of malignancy score of 10% (right craniocaudal [R CC]), shown as polygonal overlays. Without AI, six of 10 readers (60%) marked a false-positive ROI. With AI assistance, this fell to two of 10 (20%). R MLO = right mediolateral oblique.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/07/2026-07-14-radiology-mammogram-ai-auto-bias.H0bYO8QlWs.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)






