RSNA 2018 MRI Preview
By Wayne Forrest, staff writer
October 31, 2018

Our Road to RSNA preview for the RSNA 2018 meeting in Chicago continues today with MRI. One enduring attribute about MRI is that no matter how long the modality has been around, it is always in a constant state of evolution.

For example, artificial intelligence (AI) looks to have some of its greatest impact in MRI. Researchers are training AI algorithms to analyze and interpret MRI data to help radiologists do their jobs, such as in complicated cardiac MRI scans, noninvasively dissecting causes of epilepsy, determining the best course of treatment for cancer patients, and improving image quality for noncontrast coronary MR angiography.

As one would expect, the issue of gadolinium-based contrast agents (GBCAs) in MRI remains a hot-button issue for radiologists, clinicians, and researchers alike. Even with the escalating amount of research into gadolinium deposition, more questions than answers still remain about how traces of the element travel to and accumulate in brain tissue, bone, skin, and the liver. Is gadolinium's route through microbleeds in the blood-brain barrier? Or does it infiltrate into cerebrospinal fluid? Is gadolinium deposition more widespread than currently thought? And are linear GBCAs more prone to deposition than macrocyclic agents?

Without a consensus -- and perhaps even after more definitive information is achieved -- researchers will continue to explore viable alternatives to GBCAs for MRI contrast. One promising option appears to be ferumoxytol. Several scientific paper presentations at RSNA 2018 will detail how the MRI contrast agent could benefit a wide range of patients and aid in such endeavors as detecting cancer in the joints of pediatric patients. For example, one study scheduled for Chicago will allay concerns that ferumoxytol can adversely affect results from the FDG-PET portion of simultaneous PET/MRI scans.

Speaking of PET/MRI, the hybrid modality is almost a decade old. Clinicians are increasingly comfortable and adept at using PET/MRI, and the number of clinical applications for which it is utilized has increased. Several researchers will show how they are expanding the role of PET/MRI in their practices and finding ways to reduce scan time for anxious patients.

Since the theme of RSNA 2018 is "Tomorrow's radiology today," what might be the future for 7-tesla MRI? Within the last 13 months, two U.S. hospitals have begun using 7-tesla scanners for clinical use. In time, we will know how ultrahigh-field MRI can contribute more regularly to the diagnoses of neurological conditions, such as dementia and Alzheimer's disease, epilepsy, and autism.

Here we have highlighted a small sample of MRI presentations scheduled for RSNA 2018. Certainly, there are multitudes of worthwhile scientific sessions, posters, refresher courses, and educational exhibits throughout the conference to advance your knowledge and use of the modality. For more information on all the presentations, as well as their times and locations, view the RSNA 2018 meeting program.

Scientific and Educational Presentations
Breast MRI with gadolinium contrast is safe for women
Sunday, November 25 | 1:00 p.m.-1:30 p.m. | BR224-SD-SUB1 | Lakeside, BR Community, Station 1
Breast MRI with macrocyclic gadolinium-based contrast agents does not put women at risk for deposits of the agent in the brain, according to this scientific poster being presented on Sunday afternoon.
Could MRI replace CT for lung cancer screening?
Monday, November 26 | 11:50 a.m.-12:00 p.m. | SSC03-09 | Room E451A
MRI could be a more cost-effective alternative to CT for lung cancer screening, say researchers from the U.S., Switzerland, and Germany, who used a prediction model to compare the two exams.
MR angiography may reduce procedure time in prostate cases
Monday, November 26 | 11:50 a.m.-12:00 p.m. | SSC15-09 | Room E352
German researchers plan to show how 3D contrast-enhanced MR angiography can help clinicians with vascular intervention before prostatic artery embolization.
Deep learning with MRI mimics cardiac technologists
Monday, November 26 | 3:00 p.m.-3:10 p.m. | SSE04-01 | Room N226
Researchers are reporting success with a deep-learning convolutional neural network designed to localize key cardiac landmarks to help with complex examinations such as cardiac MRI.
Deep learning could aid MRI to detect mesial temporal sclerosis
Monday, November 26 | 3:10 p.m.-3:20 p.m. | SSE19-02 | Room E352
In this session, researchers will describe their early success in developing a deep-learning method featuring a convolutional neural network to help MRI detect mesial temporal sclerosis in epilepsy patients.
Can ferumoxytol MRI detect joint infiltration in pediatric cancer?
Monday, November 26 | 3:30 p.m.-3:40 p.m. | SSE21-04 | Room E353B
The MRI contrast agent ferumoxytol might serve as an indicator of the infiltration of cancer into the joints of pediatric cancer patients, according to this pilot study.
PET/MRI with ferumoxytol MR contrast performs well for pediatric patients
Monday, November 26 | 3:40 p.m.-3:50 p.m. | SSE21-05 | Room E353B
Clinicians can add a ferumoxytol contrast agent to MRI for simultaneous scans with FDG-PET in pediatric patients, with no worry about the contrast agent's effect on standardized uptakes values.
What can PET/MRI do for rectal imaging?
Tuesday, November 27 | 11:00 a.m.-11:10 a.m. | SSG09-04 | Room S505AB
Brazilian researchers will tout the clinical advantages of PET/MRI for rectal cancer and present an MRI protocol that keeps total scan time tolerable for patients.
Using deep learning, MRI may help combat common brain tumor
Tuesday, November 27 | 11:50 a.m.-12:00 p.m. | SSG10-09 | Room E353A
Combining a deep-learning algorithm with quantitative MRI could help advance treatment and survival for patients with glioblastoma multiforme.
Breast MRI tops DBT-ABVS for cancer staging
Tuesday, November 27 | 3:30 p.m.-3:40 p.m. | SSJ02-04 | Room E353C
Breast MRI performs better for breast cancer treatment staging than the combination of digital breast tomosynthesis (DBT) and ultrasound automated breast volume scanning (ABVS) -- but the latter works well enough to offer patients an alternative if MRI isn't available, Italian researchers have found.
Cardiac FDG-PET/MRI's role in Anderson-Fabry disease
Tuesday, November 27 | 3:50 p.m.-4:00 p.m. | SSJ03-06 | Room E353A
Simultaneous cardiac FDG-PET/MRI could be a welcome option for the early detection of cardiac involvement in Anderson-Fabry disease and identifying different stages of disease progression, according to researchers from Italy.
Fluorine MRI can identify veterans with respiratory issues
Tuesday, November 27 | 3:50 p.m.-4:00 p.m. | SSJ05-06 | Room S404AB
Researchers from Duke University Medical Center are exploring the use of fluorine-19 MRI to determine if soldiers are dealing with a condition known as war lung injury.
Deep-learning reconstruction improves coronary MR angiography
Wednesday, November 28 | 11:40 a.m.-11:50 a.m. | SSK03-08 | Room S102CD
In this session, Japanese researchers will share results from their newly developed deep-learning reconstruction technique designed to improve image quality for noncontrast coronary MR angiography.
Breast MRI may be good for intermediate-risk women
Wednesday, November 28 | 12:45 p.m.-1:15 p.m. | BR266-SD-WEB6 | Lakeside, BR Community, Station 6
Screening breast MRI could be an effective tool for women with an intermediate risk of breast cancer, according to this poster being presented on Wednesday afternoon.
PET/MRI works for cancer staging in pediatric patients
Wednesday, November 28 | 12:45 p.m.-1:15 p.m. | PD191-ED-WEB7 | Lakeside, PD Community, Station 7
PET/MRI has shown diagnostic value for cancer staging in adult patients, but what value does the hybrid modality provide for pediatric patients? Researchers from Stanford University answer this question in an educational exhibit.
How widespread is gadolinium accumulation in the brain?
Wednesday, November 28 | 3:00 p.m.-3:10 p.m. | SSM19-01 | Room N227B
Gadolinium accumulation in the brain may occur with both linear and macrocyclic contrast agents, and it could be more widespread than previously thought, according to researchers from Switzerland.
How to reduce MRI wait times and scan delays
Thursday, November 29 | 10:50 a.m.-11:00 a.m. | RC613-10 | Room S502AB
In this Thursday morning session, researchers from New York City will share how they reduced appointment scheduling delays and start times for pediatric MRI scans with sedation.
So, how is that PET/MRI working out for you?
Thursday, November 29 | 11:20 a.m.-11:30 a.m. | SSQ14-06 | Room S505AB
In this presentation, German researchers will look back at the clinical evolution of PET/MRI and how image acquisition times, protocol complexity, and tracer dosage have changed.
Can ferumoxytol replace gadolinium-based contrast agents?
Thursday, November 29 | 11:30 a.m.-11:40 a.m. | RC613-14 | Room S502AB
With the continuing controversy over gadolinium retention in bone, skin, liver, and portions of the brain long after contrast-enhanced MRI scans occur, exploration continues for viable alternatives, as researchers will discuss in this presentation.
CAD advances reading skills for MR angiography
Thursday, November 29 | 11:30 a.m.-11:40 a.m. | SSQ16-07 | Room S504AB
Computer-aided detection (CAD) based on deep learning can help detect unruptured cerebral aneurysms from MR angiography scans, according to researchers from Japan.
Macrocyclic GBCA shows lower signal intensity in kids
Friday, November 30 | 11:30 a.m.-11:40 a.m. | SST08-07 | Room E263
If you are still in Chicago on Friday, the issue of serial administration of a macrocyclic gadolinium-based contrast agent (GBCA) for pediatric patients will be of interest.