Body Applications of PET/CT: Not Everything You See Is Malignant

May 9th, 2016
Webinar
https://www.icpme.us
Phone:607-257-5860, ext. 29
A one-hour certified live webinar with Dr. Mukesh Harisinghani from MGH/HMS on the benefits of PET/CT for oncologic imaging; how it is used for patients with suspected or confirmed cancer; and how to differentiate between benign and malignant tissue.
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(A) Ga-68 NK224 PET/CT maximum intensity projection image (left), axial PET/CT images (center), and axial CT images (right) in a 43-year-old female participant with lung adenocarcinoma show lesions in the right cerebellum (blue arrow), right frontal lobe (red arrow), and sternum (green arrow) with low, intermediate, and high tracer uptake, respectively. Photomicrographs (scale bar, 100 μm) with hematoxylin-eosin (H&E) staining (center bottom) and programmed death ligand 1 (PD-L1) immunohistochemical (IHC) staining (right bottom) show high PD-L1 expression in the sternal lesion (tumor proportion score ≥ 50%).
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Artificial intelligence (AI) assistance facilitates correct fracture identification in cases initially missed by human readers. A representative case is shown using anteroposterior radiographs in a 29-year-old male patient with wrist trauma (suspected nondisplaced transverse scaphoid fracture). The reader’s initial unaided assessment (top) resulted in a missed fracture, whereas with AI assistance (bottom), the fracture was correctly identified. The green box represents the fracture location as predicted by the AI tool, the blue box represents the reference standard annotation, and the red dots represent individual reader annotations.
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(A) Ga-68 NK224 PET/CT maximum intensity projection image (left), axial PET/CT images (center), and axial CT images (right) in a 43-year-old female participant with lung adenocarcinoma show lesions in the right cerebellum (blue arrow), right frontal lobe (red arrow), and sternum (green arrow) with low, intermediate, and high tracer uptake, respectively. Photomicrographs (scale bar, 100 μm) with hematoxylin-eosin (H&E) staining (center bottom) and programmed death ligand 1 (PD-L1) immunohistochemical (IHC) staining (right bottom) show high PD-L1 expression in the sternal lesion (tumor proportion score ≥ 50%).
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Artificial intelligence (AI) assistance facilitates correct fracture identification in cases initially missed by human readers. A representative case is shown using anteroposterior radiographs in a 29-year-old male patient with wrist trauma (suspected nondisplaced transverse scaphoid fracture). The reader’s initial unaided assessment (top) resulted in a missed fracture, whereas with AI assistance (bottom), the fracture was correctly identified. The green box represents the fracture location as predicted by the AI tool, the blue box represents the reference standard annotation, and the red dots represent individual reader annotations.
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