Medical isotope producer Advanced Medical Isotope (AMIC) has obtained a license from the Battelle Memorial Institute for eight patents for injectable radiogel technology for use in high-dose radiation therapy.
The agreement grants AMIC an exclusive license to make, use, and sell a radiogel system, which includes an injectable, water-based biodegradable polymer that delivers yttrium-90 (Y-90) microspheres directly into tumor tissues.
The technique warms to body temperature after injection and then polymerizes into a lattice that traps the Y-90 microspheres in place. High-energy beta particles from Y-90 irradiate cancer cells within the targeted volume with very little escape of radiation.
The procedure is designed to maximize radiation dose to cancer cells and minimize radiation exposure and associated side effects to nearby normal tissues.
The license from Battelle comes after the option signed by the two companies in February 2011.
![A 53-year-old patient (patient number four) with a recurrent pituitary adenoma with extension of a cystic component of disease to the medial temporal lobe apparent on MRI (contoured in blue), and extension of disease to the left sphenoid bone and orbital apex apparent on [68Ga]Ga-DOTA-TATE (contoured in yellow).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/04/pituitary-tumor.QGsEnyB4bU.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
