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Duke MMIL designs novel SPECT/CT system for 3D breast imaging

Jul 17, 2007
2007 07 17 14 38 39 706
2007 07 17 14 38 39 706
Image courtesy of Duke University Medical Center Multi-Modality Imaging Lab.

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A 58-year-old woman was diagnosed with ER-positive (Allred score 8) ILC in her right breast. Ultrasound and MRI found prominent lymph nodes in right axillary level I area, diagnosed as metastasis on ultrasound-guided fine-needle aspiration. F-18 FES-PET/CT showed a positive mass in right breast (white arrow; SUVmax, 5.6) and multiple F-18 FES–positive lymph nodes in right axillary level I, II, and II/III junction areas (red arrows; SUVmax, up to 12.2). In addition, a small F-18 FES-positive lymph node was observed in the right second internal mammary area (red circles; SUVmax, 1.8). However, biopsy could not be performed because it was too small and not visible on ultrasound; the clinician decided to include internal mammary lymph node in treatment field for adjuvant radiotherapy. The patient underwent lumpectomy with ALN dissection, with five metastases being identified in 13 lymph nodes dissected, and is scheduled to receive adjuvant chemotherapy, radiotherapy, and endocrine therapy.
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