The American Cancer Society (ACS) has released a new guideline for colorectal cancer screening recommending that screening should begin at 45 years of age instead of 50.
In a study led by the ACS, researchers found that clinicians reported new cases of colorectal cancer in young and middle-aged adults at a steadily increasing rate in the U.S. from 1974 to 2013. Incidence rates have gone up by as much as 3% per year in individuals between the ages of 20 and 54 (Journal of the National Cancer Institute, February 28, 2018).
The society has updated its colorectal cancer screening guideline in light of these and similar findings. The new recommendations include the following:
- Individuals at average risk of colorectal cancer should start screening at 45 years.
- Healthy individuals with a life expectancy of more than 10 years should continue regular screening through the age of 75.
- Individuals between 76 years and 85 years should seek screening on a case-by-case basis.
- Individuals older than 85 years should avoid screening.
The recommended screening exams for colorectal cancer include CT colonography, colonoscopy, flexible sigmoidoscopy, and various stool-based tests.



















![Images show the pectoralis muscles of a healthy male individual who never smoked (age, 66 years; height, 178 cm; body mass index [BMI, calculated as weight in kilograms divided by height in meters squared], 28.4; number of cigarette pack-years, 0; forced expiratory volume in 1 second [FEV1], 97.6% predicted; FEV1: forced vital capacity [FVC] ratio, 0.71; pectoralis muscle area [PMA], 59.4 cm2; pectoralis muscle volume [PMV], 764 cm3) and a male individual with a smoking history and chronic obstructive pulmonary disorder (COPD) (age, 66 years; height, 178 cm; BMI, 27.5; number of cigarette pack-years, 43.2, FEV1, 48% predicted; FEV1:FVC, 0.56; PMA, 35 cm2; PMV, 480.8 cm3) from the Canadian Cohort Obstructive Lung Disease (i.e., CanCOLD) study. The CT image is shown in the axial plane. The PMV is automatically extracted using the developed deep learning model and overlayed onto the lungs for visual clarity.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/03/genkin.25LqljVF0y.jpg?auto=format%2Ccompress&crop=focalpoint&fit=crop&h=112&q=70&w=112)