Astellas releases Lexiscan stress agent

Astellas Pharma U.S. is making Lexiscan (regadenoson) injection available for use as a pharmacologic stress agent in radionuclide myocardial perfusion imaging (MPI) for patients unable to undergo exercise stress.

The Deerfield, IL, company codeveloped Lexiscan with CV Therapeutics of Palo Alto, CA.

MPI identifies areas of poor blood flow in the heart to determine the extent and characteristics of coronary artery disease. In two identical phase III clinical trials, Lexiscan met primary goals for scan agreement rates by showing 95% confidence that MPI studies with Lexiscan were similar to MPI studies with Astellas' Adenoscan stress agent.

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Heart-imaging agent gets FDA approval, April 14, 2008

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