By Kate Madden Yee, staff writer
November 10, 2010

Monday, November 29 | 9:05 a.m.-9:15 a.m. | VM21-04 | Arie Crown Theater
Breast-specific gamma imaging (BSGI) improves the detection of breast cancer, but the modality doesn't do away with the need for biopsy when indicated by mammography or ultrasound, according to researchers from Weinstein Imaging Associates in Pittsburgh.

In this Monday morning scientific session, Barbara Ward, MD, and colleagues will present findings from their study that compared the sensitivity and specificity of mammography, ultrasound, and BSGI in their clinical practice.

The study included 123 patients with 128 lesions (111 of which were benign and 17 of which were malignant). Seventy-seven percent of the women included had dense breasts, and 46% were at indeterminate risk or high risk or had a personal history of breast cancer. Two cancers were found with all three modalities, and four were found on BSGI and mammography but not ultrasound. In addition, seven were found with BSGI alone and four with mammography alone.

Ward's team found that sensitivity and specificity for BSGI were 76% and 75%, respectively. For mammography, sensitivity and specificity were 56% and 67% respectively, and for ultrasound, the values were 12% and 90%, respectively. The team concluded that BSGI is a helpful, complementary modality for finding breast cancer, but it's not so effective as to obviate the need for biopsy when indicated by mammography or ultrasound.

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