Wayne Forrest

MRI
Cardiac MRI offers prognosis for hard-to-find infarctions
Cardiac MRI can play a critical role in helping to determine which patients suspected of having stable coronary artery disease could have an unrecognized myocardial infarction and an increased risk of an adverse cardiac event, according to a study published online recently in PLOS One.
July 17, 2018
2018 07 17 21 46 8735 Lge Cardiac Mri Plos One 20180717211523
Nuclear Medicine
PET could make synaptic density an Alzheimer's biomarker
Researchers from Yale University are reporting promising results with a PET tracer designed to assess synaptic density in patients with Alzheimer's disease. The hope is that the approach could become an in vivo biomarker for dementia and help in therapy development, according to a paper published online July 16 in JAMA Neurology.
July 17, 2018
2017 04 14 16 09 55 745 Amyloid Plaque Alzheimer 400
MRI
MRI links iron in the brain to multiple sclerosis
Lower levels of iron in the thalamus as seen on MRI scans of people with multiple sclerosis are a strong indication that the disease will progress and lead to greater disability, according to a study published online July 17 in Radiology.
July 17, 2018
2018 07 16 23 35 1572 Iron 400
Nuclear Medicine
Women's menstrual phase may increase radiation risk
Hormonal changes caused by a woman's menstrual cycle may put them at higher risk of developing cancer from exposure to medical radiation, according to a letter published July 10 in Radiology. Providers may want to consider menstrual phase when deciding when to perform studies -- particularly nuclear medicine exams -- in younger women, the researchers recommended.
July 12, 2018
2015 10 14 09 24 36 945 Radiation Symbol 200 New
Nuclear Medicine
C-11-based PET tracer could benefit arthritis patients
Carbon-11 (C-11) PET that targets translocator protein expression in the joint lining tissue of the knee may be a better way to determine the extent of rheumatoid arthritis, according to a study published in the July issue of the Journal of Nuclear Medicine.
July 8, 2018
2018 07 09 20 58 3332 Jnm Narayan Pet Images 400
Nuclear Medicine
Time-of-flight PET can reduce radiation dose in pediatrics
By adding a time-of-flight technique to pediatric PET scans, clinicians can adjust radiation dose levels by as much as 50% with no discernible loss of diagnostic image quality, according to a study presented at the Society of Nuclear Medicine and Molecular Imaging annual meeting in Philadelphia.
July 8, 2018
2018 07 06 22 01 6839 Snmmi Tof Petmri 20180706225233
MRI
MRI brain scans show benefits of prenatal folic acid
MRI scans show that adolescents whose mothers received food enriched with folic acid while they were pregnant have enhanced brain development and a reduced risk of psychosis and other mental illnesses as they progress toward adulthood, according to a study published online July 3 in JAMA Psychiatry.
July 3, 2018
2018 07 03 00 33 6652 Roffman Folic Acid 400
MRI
MRI links inflammation to cognitive decline
Using MRI, researchers have found that chronic inflammation measured by a biomarker in the blood of middle- to late-age adults could be linked to visible white-matter damage in the brain and related poor cognition and dementia, according to a study in the August issue of Neurobiology of Aging.
July 2, 2018
2018 07 03 17 17 9920 White Matter Johns Hopkins 400
Nuclear Medicine
Novel nanoSPECT/CT radionuclide could aid cancer therapy
Swedish and Dutch researchers are reporting early progress in combining nanoSPECT/CT with a novel pretargeted radionuclide therapy for cancer that so far is nontoxic to the kidneys, according to a preclinical study published in the July issue of the Journal of Nuclear Medicine.
July 2, 2018
2018 07 02 21 04 7999 Jnm Mice Nano Spect Ct Image 215
MRI
Macrocyclic GBCA shows no signal increase in kids
Five or more doses of the macrocyclic gadolinium-based contrast agent (GBCA) gadobutrol resulted in no increase in T1-weighted signal-intensity ratios in the globus pallidus or dentate nucleus of pediatric patients, a sign of no gadolinium deposition in these patients, according to a June 26 paper in Radiology.
June 29, 2018
2016 10 04 14 10 28 621 Gadolinium 400
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New PET tracer developed for breast cancer
By Will Morton
A new PET radiotracer shows promise for diagnosing triple-negative breast cancer.
February 14, 2025
Ga-68 FZ-NR-1 PET/CT images and F-18 FDG PET/CT and PET/MRI images in representative nectin-4-positive TNBC patients. (A) PET/CT images and nectin-4 immunohistochemistry (IHC) staining of patient 1. Maximum-intensity projection (MIP) images and axial and coronal PET/CT images of Ga-68 FZ-NR-1 and F-18 FDG both showed high uptake in lung metastases (arrow). (B) PET/CT images and nectin-4 IHC staining of patient 2. MIP images and axial and coronal PET/CT images of Ga-68 FZ-NR-1 showed high uptake in recurrence of right breast cancer after surgery (arrow), and those of F-18 FDG PET/MRI showed high uptake. Image courtesy of the Journal of Nuclear Medicine.
Public trust in medical AI use low
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Trust is low among U.S. adults when it comes to healthcare systems using AI responsibly and protecting patients from AI-related harms.
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Pluvicto safe in patients with impaired kidneys
By Will Morton
Lu-177 prostate-specific membrane antigen-617 (Lu-177 PSMA-617, Pluvicto) may be safely delivered in patients with impaired renal function.
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Lung lesion volume doubling times associated with survival metrics
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Tracking volume doubling times of the solid component of lung adenocarcinomas can help clinicians predict patients' recurrence-free survival.
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fMRI reveals a brain circuit for creativity
By Kate Madden Yee
Functional MRI (fMRI) has revealed a brain circuit for creativity, researchers from Mass General Brigham in Boston have reported.
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DCR shows promise in patients with cystic fibrosis
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Dynamic chest radiography (DCR) shows potential as a tool to investigate lung health in people with cystic fibrosis.
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HPI: Radiologist supply, imaging demand will contribute to future workforce shortage
By Kate Madden Yee
Unless mitigating measures are taken, the current supply of radiologists in the U.S. and increased demand for imaging will likely lead to a continuing workforce shortage in the future.
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Ultrasound rules out N2 disease in PET-negative lung cancer patients
By Amerigo Allegretto
Combined endobronchial ultrasound and endoscopic ultrasound is a reliable tool for ruling out N2 disease in PET-negative lung cancer patients.
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AI model annotates pediatric AXR reports
By Will Morton
A large language model called Axpert demonstrates potential for automatically labeling necrotizing enterocolitis on infant abdominal x-ray (AXR) reports.
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Ai 1
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