Fourth-quarter revenues will be above expectations for point-of-care ultrasound developer Butterfly Network, according to preliminary results.
The company expects that revenue in the fourth quarter (end-December 31) will range from approximately $17.9 million to $18.9 million, representing an increase of about 14% to 21%. Butterfly anticipates that 2021 revenue will range between $61.5 million to $62.5 million, up approximately 33% to 35% from 2020 revenues. Butterfly had previously issued revenue guidance in the range of $60 million to $62 million for 2021.
In other news, Butterfly has inked a deal with the University of Rochester Medical Center for an enterprise-wide deployment of its Blueprint ultrasound platform. The institution is expected to begin rolling out Blueprint this summer and begin providing handheld imaging units this fall to second- and third-year medical students, primary care providers, and home care nurses.
In the future, URMC and Butterfly plan to pursue multiple research projects involving image analysis, artificial intelligence (AI), and clinical pathways. What's more, they will focus on education and curriculum for point-of-care ultrasound, creation of encounter-based workflows, development of best practices for deployment, infrastructure integration, compliance, quality assurance, and 3D procedural guidance, according to Butterfly. The agreement marks the firm's first enterprise-wide contract.
![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
