A new study supports the first-line role of cervical spine x-ray as a screening exam in pediatric blunt trauma patients.
The finding is from a 10-year review in which cervical spine (c-spine) x-ray screening had a sensitivity of 100% for clinically significant injuries, noted lead author William Starr, MD, of the University of Utah Health in Salt Lake City, and colleagues.
“Our study provides a large contemporary cohort where national c-spine protocols are followed showing a normal c-spine [x-ray] and a normal physical examination resulted in zero missed clinically significant injuries,” the group wrote. The study was published August 3 in Trauma Surgery & Acute Care Open.
Detection of pediatric c-spine injuries and the process by which cervical collars are removed is of the utmost importance, as missed injuries can be devastating, the authors explained. C-spine x-ray has been shown to be a valid screening tool for c-spine injury when coupled with a normal physical examination, and it is recommended by the Pediatric Trauma Society, they added.
“Despite these recommendations, [x-rays] have been abandoned as a screening tool at some institutions,” the group wrote.
Furthermore, the sensitivity and negative predictive value of c-spine x-rays have not been evaluated in a large, contemporary cohort of pediatric trauma patients, they noted.
Thus, the group conducted a retrospective review of cases at their level 1 pediatric trauma center from 2012 to 2021. The hospital’s protocol is to start with x-ray in patients with Glasgow Coma Scale (GCS) scores between 14 and 15 and then go to multidetector CT in patients with a depressed GCS score. The researchers compared a group with negative c-spine x-ray and no additional imaging to a group with negative c-spine x-ray followed by additional c-spine CT and/or MRI.
According to the results, out of 2,081 patients with negative x-rays, 1,974 (95%) had their c-spines cleared without additional imaging. The remaining 108 patients had additional c-spine imaging after negative c-spine x-ray for c-spine clearance (24 CT, 76 MRI, and 8 both CT and MRI). Indications for additional c-spine imaging were pain (48.1%), a GCS score ≤ 14 (43.5%), and paresthesia (8.3%), the researchers reported.
“In this cohort, screening [x-ray] had a sensitivity of 100% for clinically significant c-spine injuries,” they wrote.
Ultimately, although x-ray has been supported as a safe initial c-spine imaging modality for evaluable pediatric blunt trauma patients, its use remains a complex and debated topic, the authors noted. X-ray has been shown to be more cost-efficient, associated with increased quality of life, and to have a decreased radiation burden when used as the initial screening modality.
Meanwhile, in adult trauma, the utilization of x-ray has been almost completely replaced by CT, making c-spine x-ray a foreign test in many locations other than pediatric-specific centers, they wrote.
“As pediatric specialists, it is important that we continue to promote [x-ray] as an important tool in pediatric trauma,” the group concluded.
The full study is available here.



![Representative example of a 16-year-old male patient with underlying X-linked adrenoleukodystrophy. (A, B) Paired anteroposterior (AP) chest radiograph and dual-energy x-ray absorptiometry (DXA) report shows lumbar spine (L1 through L4) areal bone mineral density (BMD). The DXA report was reformatted for anonymization and improved readability. The patient had low BMD (Z score ≤ −2.0). (C) Model (chest radiography [CXR]–BMD) output shows the predicted raw BMD and Z score in comparison with the DXA reference standard, together with interpretability analyses using Shapley additive explanations (SHAP) and gradient-weighted class activation maps. The patient was classified as having low BMD, consistent with the reference standard. AM = age-matched, DEXA = dual-energy x-ray absorptiometry, RM2 = room 2, SNUH = Seoul National University Hospital, YA = young adult.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/04/ai-children-bone-density.0snnf2EJjr.jpg?auto=format%2Ccompress&fit=crop&h=100&q=70&w=100)






![Representative example of a 16-year-old male patient with underlying X-linked adrenoleukodystrophy. (A, B) Paired anteroposterior (AP) chest radiograph and dual-energy x-ray absorptiometry (DXA) report shows lumbar spine (L1 through L4) areal bone mineral density (BMD). The DXA report was reformatted for anonymization and improved readability. The patient had low BMD (Z score ≤ −2.0). (C) Model (chest radiography [CXR]–BMD) output shows the predicted raw BMD and Z score in comparison with the DXA reference standard, together with interpretability analyses using Shapley additive explanations (SHAP) and gradient-weighted class activation maps. The patient was classified as having low BMD, consistent with the reference standard. AM = age-matched, DEXA = dual-energy x-ray absorptiometry, RM2 = room 2, SNUH = Seoul National University Hospital, YA = young adult.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/04/ai-children-bone-density.0snnf2EJjr.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)







