SCCT, SCAI publish fractional flow reserve in CCTA guideline

AuntMinnie.com staff writers

Jun 8, 2026

The Society of Cardiovascular Computed Tomography (SCCT) and the Society for Cardiovascular Angiography and Interventions (SCAI) have released a guideline for the use of fractional flow reserve (FFR) in coronary CT angiography (CCTA).

The document was crafted by a team led by Jonathan Weir-McCall of King's College London in the U.K. and was published June 3 in the Journal of Cardiovascular Computed Tomography (JCCT). It has been endorsed by the American College of Cardiology (ACC), according to the journal.

Read it in full here.

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Exemplary cases from the ESCAPE-MeVO trial illustrating good, moderate, and poor collateral status at baseline multiphase CT angiography (CTA). (A) Sagittal image shows a left anterior middle cerebral artery medium-vessel occlusion (MeVO) with a calcified thrombus (arrow). (B–D) Axial images show the (B) arterial, (C) peak venous, and (D) delayed venous phases of the baseline multiphase CTA examination. The affected brain parenchyma is highlighted by the dashed outline. The collateral status is good, with early filling of more than 50% of the leptomeningeal collaterals compared with the contralateral side in the arterial phase (B), and there is no delayed washout in the peak venous (C) or delayed venous phase (D). (E) Sagittal image shows a left anterior middle cerebral artery MeVO (arrow). (F–H) Axial images show the (F) arterial, (G) peak venous, and (H) delayed venous phases of the baseline multiphase CTA examination. The affected brain parenchyma is highlighted by the dashed outline. The collateral status is moderate (more than 25% but less than 50% filling of the leptomeningeal collaterals in the affected territory compared with the contralateral side) on the arterial (F) and peak venous (G) phase, and there is delayed washout in the late venous phase (H). (I) Sagittal image shows a posterior dominant middle cerebral artery MeVO (arrow). (J–L) Axial images show the (J) arterial, (K) peak venous, and (L) delayed venous phases of the baseline multiphase CTA examination. The affected brain parenchyma is highlighted by the dashed outline. The collateral status is poor, with almost no collateral filling.

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