The radiopharmaceutical will be used in PET scans for assessing the status and progression of neurofibrillary tangles (NFTs) in the brain. NFTs made up of aggregated tau protein are a hallmark of several neurodegenerative diseases, including Alzheimer's disease, according to Cerveau.
The collaboration will use MK-6240 as an exploratory biomarker in studies on neurodegenerative disease research conducted by Alector. The companies will collaborate to evaluate the effect of therapies on the progression of neurodegenerative diseases.
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