Matthew A. Michela

PACS/VNA
Why interoperability is suddenly a very real thing
Life Image President and CEO Matthew Michela explains why healthcare IT companies must step up now to enable interoperability and digital image sharing. As the healthcare delivery system grapples with a global pandemic, the consequences of noninteroperability are very real.
May 4, 2020
2020 05 04 23 22 1021 Michela Matthew
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ASTRO 2026
ASTRO: Navigator program improves access for African American breast cancer patients
Afua Ofori-Darko, a medical student at Case Western Reserve, presented early phase I results of a structured patient navigation program.
Knee Joint Pain 400
ASTRO 2026
ASTRO: Low-dose RT tied to fewer knee replacements
Astro1
ASTRO 2026
ASTRO: Ultra-low-dose RT controls myeloma bone pain
Thomas DeLaney, MD, delivered a talk at ASTRO September 27 on preserving limbs in patients with extremity sarcoma.
ASTRO 2026
ASTRO: Limb-sparing care now standard for extremity sarcoma
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ASTRO: Navigator program improves access for African American breast cancer patients
By Will Morton
Afua Ofori-Darko, a medical student at Case Western Reserve, presented early phase I results of a structured patient navigation program.
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ASTRO: Low-dose RT tied to fewer knee replacements
By Amerigo Allegretto
Patients who underwent low-dose RT had longer symptom relief, less joint deterioration, and lower disability risk.
September 27, 2026
Knee Joint Pain 400
ASTRO: Ultra-low-dose RT controls myeloma bone pain
By Will Morton
The pain response rate was 59% at four weeks.
September 27, 2026
Astro1
ASTRO: Limb-sparing care now standard for extremity sarcoma
By Will Morton
In the 1970s, over 50% of extremity soft tissue sarcomas were treated by amputation.
September 27, 2026
Thomas DeLaney, MD, delivered a talk at ASTRO September 27 on preserving limbs in patients with extremity sarcoma.
ASTRO: Siemens unveils Accela radiotherapy system
By AuntMinnie.com staff writers
NeoArc allows stereotactic treatment to be delivered within a single breath hold.
September 27, 2026
Siemens Healthineers' Accela radiotherapy system
ASTRO: Proton RT controls high-risk neuroblastoma
By Will Morton
Findings support PRT as a strategy to reduce long-term morbidity without compromising oncologic outcomes.
September 26, 2026
Astro 2026 Thumb 2
ASTRO: How does tumor location affect survival in patients with esophageal cancer?
By Will Morton
Upper esophageal tumors were associated with the best survival, while middle esophageal location carried significantly worse odds.
September 26, 2026
Astro 2026 Thumb
CT-based AI model predicts pneumonitis in lung cancer patients
By Amerigo Allegretto
The algorithm outperformed clinical and radiomics models in these patients.
September 25, 2026
CIPHER, an AI-powered CT foundation model, identifies patients with lung cancer at increased risk of immunotherapy-induced pneumonitis before treatment begins. The AI-generated output, shown here, highlights lung abnormalities to support early risk assessment and personalized patient care.
Women's Imaging MinnieCast, Episode 18: On the road with the LBCA
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The Lobular Breast Cancer Alliance (LBCA) is embarking on a nationwide bus tour to raise disease awareness.
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What are the effects of COVID-19 pneumonia after 5 years?
By Will Morton
After five years, residual lesions persisted in 35.6% of survivors (37 of 104).
September 24, 2026
Representative longitudinal chest CT images and five-year parametric response mapping (PRM), pulmonary vascular CT reconstructions, and hyperpolarized xenon-129 (Xe-129) ventilation MRI scans from survivors of nonsevere and severe COVID-19 pneumonia. (A–F) Images in a 68-year-old male survivor of nonsevere COVID-19 pneumonia, (G–L) 62-year-old male survivor of severe COVID-19 pneumonia, and (M–R) 55-year-old male survivor of severe COVID-19 pneumonia. For each participant, the first three columns show coronal chest CT images from the acute phase (A, G, M), two-year follow-up (B, H, N), and five-year follow-up (C, I, O) (left to right). The fourth column (D, J, P) shows a coronal PRM image for each participant at five-year follow-up derived from paired inspiratory and expiratory CT scans, showing the spatial distribution of lung functional categories. Green indicates normal lung tissue, yellow indicates functional small airway disease, and red indicates emphysema. The second-to-last column shows volume-rendered small pulmonary vessel visualization (red) at five-year follow-up per participant (E, K, Q). The column on the far right (F, L, R) shows a hyperpolarized Xe-129 MRI ventilation defect percentage (VDP) map at five-year follow-up per participant. Dark blue represents high Xe-129 signal intensity, corresponding to well-ventilated lung regions, whereas red represents no Xe-129 signal intensity, corresponding to ventilation defects. At five-year follow-up, the 68-year-old survivor of nonsevere COVID-19 pneumonia (top row) showed near-complete radiologic resolution, no respiratory symptoms, and preserved pulmonary function. In contrast, the 62-year-old survivor of severe COVID-19 pneumonia (middle row) showed persistent fibrotic linear opacities without respiratory symptoms and mildly reduced pulmonary function. The 55-year-old survivor of severe COVID-19 pneumonia (bottom row) showed persistent scattered fibrotic linear opacities and focal emphysematous changes in both lungs, with dyspnea and impaired gas exchange function. The VDP values obtained from F, L, and R were 7.7%, 7.1%, and 6.3%, respectively.
USC researchers develop “plug-and-play" platform for PET tracers
By Will Morton
Preliminary work suggests the approach can generate tracers targeting fibroblast activation protein.
September 24, 2026
Nuclear Medicine
Image-based grading system estimates nasopharyngeal carcinoma severity
By Amerigo Allegretto
The four-tier grading system showed excellent reliability and good prognostic value for patients with nasopharyngeal carcinoma.
September 23, 2026
Representative MRI scans for which the independently assigned imaging-derived extranodal extension (iENE) grades differed among the readers. (A) Axial and sagittal images in a 56-year-old male patient with nasopharyngeal carcinoma and cervical nodal metastases. Readers 1 and 3 interpreted the finding as a metastatic lymph node invading the left sternocleidomastoid muscle (arrow) and assessed an iENE grade of 3, whereas reader 2 assigned a grade of 2. After joint review, the radiologists reached a consensus on the absence of definite sternocleidomastoid muscle invasion, and the final iENE grade was 2. (B) Axial and sagittal images in a 52-year-old male patient with nasopharyngeal carcinoma and cervical nodal metastases. Reader 1 interpreted the findings as a single enlarged metastatic lymph node and assessed an iENE grade of 1, whereas readers 2 and 3 interpreted them as two coalescent metastatic lymph nodes (arrows) and assessed a grade of 2. After joint review, the radiologists reached a consensus on the coalescence of the two metastatic lymph nodes, and the final iENE grade was 2.
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