Diana Roettger, PhD, and Olga Kubassova, PhD

MRI
Advanced imaging offers insight into targeted therapies
Major breakthroughs are emerging in the development of targeted therapies that use the body's own immune system to attack cancer cells. But traditional methods of measuring the success of drug candidates are slow and expensive. Could advanced imaging help? Diana Roettger, PhD, and Olga Kubassova, PhD, of the Image Analysis Group offer a perspective.
February 5, 2019
2019 02 04 22 19 8026 Gbm Before 250
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CT
Understanding CT flow artifacts is key to better disease diagnosis
Understanding the mechanics of flow artifacts on CT or CT angiography and how these artifacts are created is key to better disease diagnosis.
Liver Cancer
Molecular Imaging
Dual-tracer PET/CT shows promise in liver cancer patients
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Womens Imaging
Studies lacking for trans breast cancer screening trends
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Artificial Intelligence
ChatGPT performs poorly on ACR exam for residents
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Understanding CT flow artifacts is key to better disease diagnosis
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Understanding the mechanics of flow artifacts on CT or CT angiography and how these artifacts are created is key to better disease diagnosis.
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Studies lacking for trans breast cancer screening trends
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SPECT/CT predicts foot amputations in diabetics
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Technetium-99m white blood cell SPECT/CT imaging may be useful for identifying diabetic patients at risk of amputations due to foot infections.
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Examples in two patients. (Top) Abnormal leukocyte accumulation was observed in the right 1st to 5th toes, with the radioactive lesions extending to the bone, indicating osteomyelitis (left panel, MIP image; right panel, axial SPECT/CT). Two spherical VOIs were drawn on diabetic foot infections (DFIs) and the highest SUVmax was 4.2 (higher than the cutoff of 1.1) Despite intensive treatment, the infection progressed, leading to the patient undergoing right below knee amputation 43 days after SPECT/CT. (Bottom) Mild focal abnormal leukocyte accumulation was detected in the right 3rd and 4th toes. The lesions were in contact with the bone, which raised a suspicion of osteomyelitis (left panel, MIP image; right panel, axial SPECT/CT). A circular VOI was drawn on DFIs and the SUVmax was 1.0 (lower than the cutoff of 1.1). After 10 weeks of antibiotic treatment, the infection was successfully resolved, and the foot was preserved. Image and caption courtesy of Scientific Reports.
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