Priscilla Butler

CT
8 strategies to optimize radiation dose in CT
How can imaging providers optimize CT dose to maximize the risk-benefit ratio and deliver better patient care? In this article, Priscilla Butler from the American College of Radiology offers eight actionable strategies for managing radiation dose while still providing diagnostic quality and accuracy.
July 13, 2017
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Shown is a 69-year-old man with a cholangiocarcinoma in the distal common bile duct. F-18 FDG-PET/CT was negative where Ga-68 FAPI-46 PET/CT showed high focal FAPI uptake in the liver hilum and surrounding lymph nodes. a-d: F-18 FDG-PET/CT, e-h: Ga-68 FAPI-46 PET/CT. a, b, e, f: Maximum intensity projections, c, g: axial fusion images, d, h: non-contrast enhanced CT.
Molecular Imaging
FAPI-PET/CT shows promise in hepatopancreatobiliary cancers
FAPI-PET/CT could potentially improve noninvasive cancer staging, and, ultimately, clinical decision making.
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Longitudinal DBT could help improve long-term cancer risk prediction
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FAPI-PET/CT shows promise in hepatopancreatobiliary cancers
By Will Morton
FAPI-PET/CT could potentially improve noninvasive cancer staging, and, ultimately, clinical decision making.
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Shown is a 69-year-old man with a cholangiocarcinoma in the distal common bile duct. F-18 FDG-PET/CT was negative where Ga-68 FAPI-46 PET/CT showed high focal FAPI uptake in the liver hilum and surrounding lymph nodes. a-d: F-18 FDG-PET/CT, e-h: Ga-68 FAPI-46 PET/CT. a, b, e, f: Maximum intensity projections, c, g: axial fusion images, d, h: non-contrast enhanced CT.
Longitudinal DBT could help improve long-term cancer risk prediction
By Amerigo Allegretto
A longitudinal DBT model outperformed other models based on mammography and clinical factors in predicting five-year cancer risk.
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SBRT for prostate cancer cuts side effects, falls short on disease control
By Will Morton
A multinational team evaluated SBRT against moderately hypofractionated intensity-modulated radiation therapy in a phase III trial.
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DEXA reveals tea consumption supports bone health
By Will Morton
Moderate-frequency tea consumption was associated with better bone mineral status and more favorable longitudinal changes.
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AI tools may not meet breast radiologists' expectations in practice
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AI tools in breast imaging may have more modest clinical impact on recall and biopsy rates.
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Stepped reminders boost CT lung cancer screening
By Will Morton
Trial findings directly address the current lack of effective lung cancer screening interventions.
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Model confidence, reader expertise affect reader-LLM collaboration
By Amerigo Allegretto
Successful human-LLM collaboration is associated with model confidence and reader expertise in chest imaging.
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Example cases illustrate the double-edged role of large language model (LLM) rationale quality. (A) A 50-year-old female patient with a palpable anterior chest wall mass (correct diagnosis: solitary fibrous tumor of the pleura). The LLM incorrectly suggested synovial sarcoma but provided a persuasive rationale (quality score: 4 of 5), describing a well-defined nodule at axial contrast-enhanced CT spanning the pleura and intercostal space with heterogeneous strong enhancement. Four of five readers (80%) accepted the incorrect suggestion. FDG = fluorodeoxyglucose. (B) A 61-year-old male patient with diabetes presented with cough, sputum, and dyspnea (correct diagnosis: mucormycosis). The LLM correctly suggested mucormycosis with an excellent rationale (quality score: 5 of 5), integrating the reverse halo sign on serial axial CT images and rapidly progressive cavitary lesions. Three of five readers initially selected incorrect diagnoses; after LLM output, all five selected the correct diagnosis (100% acceptance). Blue and orange reader icons denote high- and low-expertise readers, respectively.
PET/CT predicts response to neoadjuvant therapy in breast cancer
By Will Morton
Monitoring neoadjuvant therapy response in HER2-positive breast cancer is challenging with existing tools.
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Ga-68 HER2-PET/CT images before neoadjuvant therapy, at end of second cycle, and before surgery. (A) Baseline scan demonstrated soft-tissue lesion measuring approximately 2.3 × 2.2 cm in upper outer quadrant of left breast, with marked radiotracer uptake and SUVmax of 10.1. (B) At end of second cycle, imaging revealed residual lesion of approximately 2.2 × 1.0 cm in same region, without abnormal radiotracer accumulation. (C) Preoperative imaging demonstrated further reduction in lesion size to approximately 2.0 × 0.6 cm, with no abnormal tracer uptake detected.
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NME breast lesions have high malignancy rate on MRI-guided biopsy
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Biopsies from women with a known ipsilateral malignancy have a higher frequency of breast cancer.
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Many women interested in AI-based risk assessment for breast cancer
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Survey findings also show that most women at higher risk are interested in additional screening tests.
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CT 5-star quality rating system supports optimization
By Will Morton
The rating framework demonstrated robust reproducibility, with three-reader concordance reaching up to 93% in highly standardized centers.
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