Luc Faucher

Molecular Imaging
Gadolinium oxide nanoparticles enhance MRI contrast
Ultrasmall gadolinium oxide nanoparticles provide strong positive contrast enhancement at clinical magnetic field strengths. For this reason, they are being developed as positive contrast agents for molecular and cellular MRI.
November 23, 2011
2011 11 23 12 58 06 797 Faucher Nanoparticles Mri Thumb
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AI-acquired standardized planes. Example ultrasound images acquired in clinical settings with the on-cart, AI-based software, illustrating automated acquisition and anatomic annotation of three standard planes: (A) S5 dorsal longitudinal plane of the wrist joint, (B) S11 transverse section of the proximal carpal tunnel, and (C) S14 transverse section of the second and third flexor tendons. A1 = trochlea A1, Cap = capitate, C-M.JS = recess of the capitate-metacarpal joint, D&Ss = flexor digitorum profundus and superficialis tendons, FCR = flexor carpi radialis tendon, FD = flexor digitorum tendon, FPL = flexor pollicis longus tendon, L-C.JS = recess of the lunate-capitate joint, Lun = lunate, MN = median nerve, Pis = pisiform, Rad = radius, R-C.JS = recess of the radiocarpal joint, Sca = scaphoid, UA = ulnar artery, UN = ulnar nerve, 3rd Met = third metacarpal.
Ultrasound
MSK AI tool for ultrasound shows promise for assisting novice imagers
The software evaluated for standard plane recognition and automatic key anatomy segmentation.
Network-level analysis comparing functional association strength between ROIs of pre- and postmenopausal groups. Lower levels of connectivity were identified among one cluster (F3,106 = 8.84, Puncorrected < 0.001, PFDR = 0.012) in the postmenopausal group, which included the right supramarginal gyrus anterior division, right planum temporale, and right Heschl’s gyrus, among others. FDR, false discovery rate; ROI, region of interest.
MRI
fMRI reveals postmenopausal brain connectivity shifts in midlife women
Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).
CT
Air pollution tied to worse coronary disease on CT, especially in women
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Imaging Informatics
SIIM: Quality management needed for successful use of imaging AI
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MSK AI tool for ultrasound shows promise for assisting novice imagers
By Liz Carey
The software evaluated for standard plane recognition and automatic key anatomy segmentation.
June 9, 2026
AI-acquired standardized planes. Example ultrasound images acquired in clinical settings with the on-cart, AI-based software, illustrating automated acquisition and anatomic annotation of three standard planes: (A) S5 dorsal longitudinal plane of the wrist joint, (B) S11 transverse section of the proximal carpal tunnel, and (C) S14 transverse section of the second and third flexor tendons. A1 = trochlea A1, Cap = capitate, C-M.JS = recess of the capitate-metacarpal joint, D&Ss = flexor digitorum profundus and superficialis tendons, FCR = flexor carpi radialis tendon, FD = flexor digitorum tendon, FPL = flexor pollicis longus tendon, L-C.JS = recess of the lunate-capitate joint, Lun = lunate, MN = median nerve, Pis = pisiform, Rad = radius, R-C.JS = recess of the radiocarpal joint, Sca = scaphoid, UA = ulnar artery, UN = ulnar nerve, 3rd Met = third metacarpal.
fMRI reveals postmenopausal brain connectivity shifts in midlife women
By Kate Madden Yee
The findings suggest that menopause represents "an important neurological transition," researchers noted.
June 9, 2026
Network-level analysis comparing functional association strength between ROIs of pre- and postmenopausal groups. Lower levels of connectivity were identified among one cluster (F3,106 = 8.84, Puncorrected < 0.001, PFDR = 0.012) in the postmenopausal group, which included the right supramarginal gyrus anterior division, right planum temporale, and right Heschl’s gyrus, among others. FDR, false discovery rate; ROI, region of interest.
Air pollution tied to worse coronary disease on CT, especially in women
By Kate Madden Yee
The strongest effects of pollution exposure is seen in women, even at moderate levels typical of high-income countries.
June 9, 2026
Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).
SIIM: Quality management needed for successful use of imaging AI
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AI may provide early breast cancer alerts from mammograms
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Commercial AI systems could provide early alerts for breast cancer by picking out early signs of the disease on mammograms.
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Screening mammograms and AI score changes are depicted over time in two individuals with screen-detected cancer. Full-field digital mammograms show craniocaudal (top) and mediolateral (bottom) views of the left and right breast. The description below each mammogram indicates whether AI scores from three AI-based computer-aided detection systems (AI-1, AI-2, and AI-3) were above or below the 90th percentile. (A) Mammograms from three screening time points (in 2009, 2011, and 2014) in an individual who was diagnosed in February 2014 (at age 73 years) with a left-sided 25-mm grade 2 invasive breast carcinoma, no special type (arrow). Mammographic breast density was classified as BI-RADS B on all three mammograms. (B) Mammograms from four screening time points (in 2009, 2011, 2013, and 2015) in an individual who was diagnosed in October 2015 (at age 65 years) with a left-sided 45-mm grade 2 lobular carcinoma (arrow). Mammographic breast density was classified as BI-RADS C on all four mammograms. Screen-detected cancers were defined as those diagnosed within 90 days for individuals who were recalled at screening (*).
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Abdominal aortic calcification (AAC) score grading: 0 - no calcific deposits in front of the vertebrae; 1 - small scattered calcific deposits filling less than 1/3 of the longitudinal wall of the aorta; 2 - 1/3-2/3 of the wall calcified; 3 - 2/3 or more of the wall calcified.
Most women with BACs have no MACE history
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Many women with BACs on mammography likely have no history of MACE, researchers found.
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More than two out of three ductal DCIS sizes are radiologically either over- or underestimated on x-ray imaging.
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What side effects do patients report after Pluvicto therapy?
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Post-Pluvicto SPECT/CT with axial fused images of sacrum and sagittal maximum intensity projection of one of the patients who complained of increasing pain in the sacral region (arrows) post therapy.
Brain SPECT offers insight into suicide risk
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Study results show that a single resting-state scan yields individualized risk trajectories that identify high-risk patients.
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