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Serial axial chest CT scans demonstrating the longitudinal evolution of small pure ground-glass nodules (pGGNs) incidentally detected during a routine wellness assessment. (A) Images in a 37-year-old woman with a family history of lung cancer show a nodule with the progressive growth pattern (box). The baseline CT scan, obtained in October 2017, demonstrates a pure ground-glass nodules in the right lower lobe. Consecutive CT scans obtained from 2017 to 2022 show the continuous enlargement of the nodule during active surveillance. The maximum diameter of the nodule increased from 5.6 mm in 2017 to 10.2 mm in 2022. (B) Images in a 45-year-old man show a nodule with the indolent growth pattern (box). The baseline CT scan, obtained in April 2018, demonstrates a pure ground-glass nodules in the left lower lobe. Consecutive CT scans obtained from 2019 to 2023 show that the nodule remained radiographically stable during CT surveillance. The maximum diameter of the nodule was 5.4 mm in 2018 and 6.1 mm at the final surveillance scan in 2023.
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CT reveals progressive growth pattern in incidental lung nodules
By Will Morton
This pattern is most associated with a family history of lung cancer.
August 25, 2026
Serial axial chest CT scans demonstrating the longitudinal evolution of small pure ground-glass nodules (pGGNs) incidentally detected during a routine wellness assessment. (A) Images in a 37-year-old woman with a family history of lung cancer show a nodule with the progressive growth pattern (box). The baseline CT scan, obtained in October 2017, demonstrates a pure ground-glass nodules in the right lower lobe. Consecutive CT scans obtained from 2017 to 2022 show the continuous enlargement of the nodule during active surveillance. The maximum diameter of the nodule increased from 5.6 mm in 2017 to 10.2 mm in 2022. (B) Images in a 45-year-old man show a nodule with the indolent growth pattern (box). The baseline CT scan, obtained in April 2018, demonstrates a pure ground-glass nodules in the left lower lobe. Consecutive CT scans obtained from 2019 to 2023 show that the nodule remained radiographically stable during CT surveillance. The maximum diameter of the nodule was 5.4 mm in 2018 and 6.1 mm at the final surveillance scan in 2023.
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True-positive PSMA-PET with positive MRI in 74-year-old male with prostate cancer (Gleason score of 4 + 5; left anterior and posterior apex positive cores). (A) Left posterior peripheral apical to midprostate hyposignal visible on transaxial MRI. (B) No definite CT correlate evident (white arrow). (C) Focal high PSMA expression detectable in left posterior mid to base with SUVmax of 12.4 on transaxial fused delayed pelvic PET/CT (yellow arrow). (D) Focal high PSMA expression found in left midgland to base of prostate on maximum-intensity-projection image (yellow arrow).
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