Week in Review: ASTRO coverage | Pluvicto case report | Brain fog and long COVID

Dear AuntMinnie Member, 

Our coverage of the American Society for Radiation Oncology (ASTRO) annual meeting in San Francisco dominated our list of most popular stories last week. 

Can radiation therapy (RT) be useful in treating knee osteoarthritis? It can, according to a group that found that a single course of low-dose RT relieved pain in patients with mild to moderate knee osteoarthritis. 

In addition, treatment with lutetium-177 (Lu-177) PNT2002 before stereotactic body radiation therapy (SBRT) significantly improved outcomes for patients with advanced prostate cancer. Also, RT was deemed to be comparable to surgery for early-stage lung cancer. 

What’s more, researchers reported that adjuvant RT after cystectomy for muscle-invasive bladder cancer yielded lower rates of new pelvic cancer. And intensity-modulated radiation therapy (IMRT) and proton therapy both performed well in treating locally advanced throat cancer. 

Stop by our Radiation Oncology/Therapy content area for our full coverage from the meeting. 

A case report on the use of Pluvicto as a first-line treatment for late-stage prostate cancer was also of high interest to our members. In addition, PET has revealed the underlying mechanism behind brain fog in patients with long COVID. 

See below for the full list of our top stories from last week. 

1. ASTRO: Low-dose RT effective for treating knee osteoarthritis 

2. ASTRO: Lu-177 PNT2002 added to SBRT delays prostate cancer progression 

3. ASTRO: Radiation therapy comparable to surgery for early-stage lung cancer 

4. ASTRO: Trial suggests postoperative RT in high-risk bladder cancer 

5. ASTRO: Contemporary IMRT comparable to proton therapy for throat cancer 

6. ASTRO: Radiotherapy offers opportunities beyond cancer treatment 

7. ASTRO: Patient navigation needed to mitigate RT treatment disparities 

8. Case report: Pluvicto as a first-line treatment in late-stage prostate cancer 

9. PET reveals mechanism underlying brain fog in long COVID 

10. New brain MRI technique could help identify Alzheimer’s 

11. What is the real impact of the 2025 MPFS Proposed Rule on radiology practices? 

12. False-positive DBT findings differ between AI, radiologists 

13. ASTRO: Short prostate SBRT reduces side effects, but not PSA levels 

14. HPI: Radiology attrition varies by gender, specialty, and practice type

Erik L. Ridley
Editor in Chief
AuntMinnie.com