Coronary imaging developer InfraReDx of Burlington, MA, has completed $21 million in equity financing.
Funds from the financing will support the commercial launch of the LipiScan IVUS coronary imaging system, which is designed to combine and coregister grayscale intravascular ultrasound (IVUS) with InfraReDx's proprietary near-infrared (NIR) spectroscopy lipid-core plaque (LCP) detection technology.
LipiScan features proprietary optical imaging technology, which overcomes heart motion, blood interference, and vascular access to perform near-infrared spectroscopic analysis of vessels and produce a chemical map of lipid-core plaque.
Related Reading
InfraReDx gets FDA nod for IVUS system, September 1, 2010
InfraReDx announces first clinical use of LipiScan, May 16, 2008
FDA clears InfraReDx's LipiScan, April 30 2008
InfraReDx receives FDA clearance, October 19, 2006
Near-infrared spectroscopy can identify vulnerable plaques in artherosclerosis, September 29, 2002
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![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
