Monday, November 30 | 3:00 p.m.-3:10 p.m. | SSE22-01 | Room S403B
In this scientific session, researchers from the Mayo Clinic in Rochester, MN, will discuss their use of a new algorithm to reduce noise in multienergy CT scans.Photon-counting detectors can generate energy-specific images that are assigned to energy bins in relatively small ranges. The trade-off is that because each bin uses only a small portion of the available photons, image noise is greater.
This led Zhicong Yu, PhD, and colleagues to develop an iterative reconstruction algorithm aimed at reducing the noise back to normal levels.
"The purpose of this work was to develop and validate a compressed sensing iterative reconstruction technique that could reduce the noise in the bin images to levels close to that of the composite image (which uses all detected photons)," wrote study co-author Cynthia McCollough, PhD, in an email to AuntMinnie.com.
Using their spectral prior image constrained compressed sensing (PICCS) algorithm, the researchers obtained significant noise reduction, averaging 70% in the energy bin images, to the benefit of spectral CT imaging applications.
Check out this Monday afternoon session to get all the details.

















![Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/06/hanneman.r6SMLzkezo.png?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)


