Tuesday, November 30 | 10:30 a.m.-10:40 a.m. | SSG13-01 | Room S403A
A University of Chicago team will provide an update on its development of computer-aided detection (CAD) software for addressing hepatocellular carcinoma (HCC), according to this paper to be presented on Tuesday morning.While contrast-enhanced hepatic CT has been deployed to detect and characterize HCC, this can be a difficult mission. The density of HCC is often similar to that of normal liver parenchyma and benign tumors, said presenter Jianwu Xu, PhD.
To help with this dilemma, the research group has been developing a CAD scheme for HCC that makes use of both the arterial and portal-venous phases of contrast-enhanced CT.
Confirming their hypothesis, the researchers found that CAD with both of these phases of contrast-enhanced CT images achieved better performance than with only the arterial-phase image, Xu said.
"Moreover, our [CAD] scheme with both arterial and portal-venous phases of CT images achieved a very low false-positive rate with high sensitivity, which paved the way for clinical usage of [CAD] in aiding radiologists in detection of HCCs," Xu told AuntMinnie.com. "The study also suggested that we might further improve the [CAD] performance by combining other phases, such as precontrast and equilibrium phases, of hepatic CT images."
![Axial images from unenhanced calcium score cardiac CT (left) and curved planar reformation images from CT angiography (right) show that higher long-term exposure to air pollution is associated with greater coronary artery calcium and more obstructive coronary artery disease (CAD). Top row: Images in a 68-year-old male patient with higher 10-year mean ambient air pollution exposure (7.9 μg/m3 for particulate matter measuring ≤2.5 μm in diameter [PM2.5] and 17.4 parts per billion [ppb] for NO2) with extensive CAD (coronary artery calcium score [CACS] >1,000 and obstructive CAD [≥70% diameter stenosis]). Bottom row: Images in a 57-year-old female patient with lower 10-year mean ambient air pollution exposure (6.3 μg/m3 for PM2.5 and 4.6 ppb for NO2) with no CAD (CACS = 0 and no obstructive stenosis).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/06/hanneman.r6SMLzkezo.png?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
