By Kate Madden Yee, AuntMinnie.com staff writer
November 10, 2010

Monday, November 29 | 11:40 a.m.-11:50 a.m. | VM21-15 | Arie Crown Theater
In this scientific session, Johns Hopkins researchers will present study results suggesting that positron emission mammography (PEM) is a helpful tool for breast cancer surgical planning in early-stage breast cancer.

Wendie Berg, MD, PhD, and colleagues from Johns Hopkins at Green Spring Station in Lutherville, MD, will explain findings from their study that compared PEM's performance to whole-body PET and PET/CT for additional cancer detection, presurgical planning, and axillary staging.

Berg's team used data from a previous study conducted between September 2006 and November 2008, during which 388 women with newly diagnosed breast cancer who had been offered breast-conserving surgery underwent both bilateral contrast-enhanced MRI and F-18 FDG PEM. Of this 388, 179 also had whole-body PET (71 of 179) or whole-body PET/CT (108 of 179). Median index tumor size was 1.4 cm.

Of the women who had PET/CT and PEM, all had residual tumors at surgery. PEM found 103 tumors (95.4%) and PET/CT found 94 (87%). In addition, 23 of these women had additional ipsilateral cancers: PEM found 13 of these and PET/CT found three.

Of the women who had PET and PEM, 68 (96%) had residual tumors at surgery. PEM caught 63 (93%) of these 68 tumors, while PET caught 38 (56%). In addition, 15 of these women had additional cancers on the opposite breast: PEM found seven of these (47%) and PET/CT found one (6.7%).


Last Updated hh 11/5/2010 4:56:01 PM




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