Glucose-MRI technique at 7T aids tumor evaluation

By staff writers

June 23, 2017 -- German researchers are taking advantage of 7-tesla MRI scans to view glucose metabolism activity and thus identify solid or aggressively growing tumors.

The approach, developed at the German Cancer Research Center (DKFZ) in Heidelberg, combines ultrahigh-field MRI with a special method that reinforces the glucose signal to make it more distinct and selective. The imaging technique makes it possible to obtain enough signal strength to visualize changes in glucose levels in brain tissue after injection of a glucose solution.

The technique is based on the magnetization transfer effect, which has not been possible for glucose imaging in humans until now. In magnetization transfer, the signal from glucose protons is transferred to bodily water, which is measured with MRI.

In the study, physicist Patrick Schuenke and physician and physicist Dr. Daniel Paech observed changes in glucose signals in healthy brain regions and pathogenic changes in human brain cancer. Unlike PET, the glucose-MRI technique does not involve any radiation exposure for the patient.

The study was published June 16 online ahead of print in Radiology.

MRI links bipolar disease to cerebellum changes
A specialized MRI scanning protocol has detected differences in brain signals in the white matter and cerebellum of individuals with bipolar disorder...
fMRI shows how brain reacts to sugar
Functional MRI (fMRI) has shown how the brain reacts when a person is given two different kinds of sugar, and how the reaction could lead to overeating.
MRI shows that diabetes leads to loss of brain volume
MRI results suggest that the longer a patient has type 2 diabetes, the more brain volume is lost, according to research published online April 29 in Radiology....

Copyright © 2017

Last Updated np 6/23/2017 3:05:28 PM